3-羰基-1-环己羧酸合成路线

Napper, Andrew D.; Hixon, Jeffrey; McDonagh, Thomas; Keavey, Kenneth; Pons, Jean-Francois; Barker, Jonathan; Yau, Wei Tsung; Amouzegh, Patricia; Flegg, Adam; Hamelin, Estelle; Thomas, Russell J.; Kates, Michael; Jones, Stephen; Navia, Manuel A.; Saunders, Jeffrey O.; DiStefano, Peter S.; Curtis, Rory
Journal of Medicinal Chemistry, 2005 , vol. 48, # 25 p. 8045 - 8054

67-56-1甲醇+

16205-98-43-羰基-1-环己羧酸

21531-47-5

参考文献

Seo, Jai Woong; Comninos, John S.; Chi, Dae Yoon; Kim, Dong Wook; Carlson, Kathryn E.; Katzenellenbogen, John A.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 8 p. 2496 - 2511

16205-98-43-羰基-1-环己羧酸+

75-65-0叔丁醇

21531-47-5

参考文献

MERCK SHARP and DOHME CORP.; BRUBAKER, Jason; DINSMORE, Christopher J.; HOFFMAN, Dawn Marie; JUNG, Joon; LIU, Duan; PETERSON, Scott; SIU, Tony; TORRES, Luis E.; ZHANG, Hongjun; WEI, Zhongyong; SHI, Feng
Patent: WO2013/40863 A1, 2013 ;
Location in patent: Page/Page column 88 ;
WO 2013/040863 A1

67-56-1甲醇+

16205-98-43-羰基-1-环己羧酸+

18107-18-1三甲基硅烷化重氮甲烷

21531-47-5

参考文献

MERCK SHARP and DOHME CORP.; BRUBAKER, Jason; DINSMORE, Christopher J.; HOFFMAN, Dawn Marie; JUNG, Joon; LIU, Duan; PETERSON, Scott; SIU, Tony; TORRES, Luis E.; ZHANG, Hongjun; WEI, Zhongyong; SHI, Feng
Patent: WO2013/40863 A1, 2013 ;
Location in patent: Page/Page column 89 ;
WO 2013/040863 A1

16205-98-43-羰基-1-环己羧酸+

100-63-0苯肼

37964-14-02,3,4,9-四氢-1H-咔唑-2-羧酸

参考文献

HUNTER-FLEMING LIMITED
Patent: WO2006/82409 A2, 2006 ;
Location in patent: Page/Page column 15 ;

16205-98-43-羰基-1-环己羧酸

37964-14-02,3,4,9-四氢-1H-咔唑-2-羧酸

参考文献

Neurogen Corporation
Patent: US5892041 A1, 1999 ;