1,7-二-(N-叔丁氧羰基甲基)-1,4,7,10-四氮杂环十二烷合成路线 (共 6 条)
反应条件
5-palladium/activated carbon; hydrogen in acetonitrile T=20°C;
参考文献
Chemical Communications, , # 22 p. 3196 - 3198
反应条件
1: 91 percent / diisopropylethylamine / acetonitrile / 22 h / 40 - 60 °C 2: 93 percent / H2 / 10percent Pd/C / ethanol / 48 h / 1034.3 - 1292.9 Torr View Scheme
参考文献
Synthesis, , # 7 p. 759 - 763
反应条件
1: 91 percent / diisopropylethylamine / acetonitrile / 22 h / 40 - 60 °C 2: 93 percent / H2 / 10percent Pd/C / ethanol / 48 h / 1034.3 - 1292.9 Torr View Scheme
参考文献
Synthesis, , # 7 p. 759 - 763
反应条件
1: 88 percent / pH 2-3 2: iPr2NEt / acetonitrile / 20 h / 60 °C 3: H2 / Pd-C / ethanol / 24 h View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 2 p. 185 - 186
反应条件
1: chloroform / 10 h / 0 - 20 °C / Cooling with ice 2: N-ethyl-N,N-diisopropylamine / acetonitrile / 10 h / 60 °C 3: hydrogen / palladium 10 on activated carbon / ethanol / 12 h / 20 °C View Scheme
反应条件
triethylamine in DMF (N,N-dimethyl-formamide) T=24.84°C; 14 - 20 h; Product distribution / selectivity;
参考文献
WO2005/3105 A1, ;
Page/Page column 6 ;