(3-环丙烷羰基苯基)-氨基甲酸苄酯合成路线 （共 3 条）
反应条件
1: 50 percent / fuming 90percent nitric acid / 0.17 h / -10 °C 2: hydrogen / 5percent platinum on carbon / methanol / 5 h / 760 Torr 3: diisopropylethylamine / CH2Cl2 / 4 h / Ambient temperature View Scheme
参考文献
Thaisrivongs, Suvit; Watenpaugh, Keith D.; Howe, W. Jeffrey; Tomich, Paul K.; Dolak, Lester A.; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 18 p. 3624 - 3637
反应条件
1: hydrogen / 5percent platinum on carbon / methanol / 5 h / 760 Torr 2: diisopropylethylamine / CH2Cl2 / 4 h / Ambient temperature View Scheme
参考文献
Thaisrivongs, Suvit; Watenpaugh, Keith D.; Howe, W. Jeffrey; Tomich, Paul K.; Dolak, Lester A.; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 18 p. 3624 - 3637
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane 4 h; Ambient temperature; Yield given;
参考文献
PHARMACIA and UPJOHN COMPANY
Patent: EP1203770 A1, 2002 ;
Location in patent: Page 58 ;
