9, 10-二氢-4H-苯并[4, 5]环庚三烯[1, 2-b]噻吩-4-酮合成路线 （共 15 条）
反应条件
PPA in xylene T=120 - 130°C; 2 h;
参考文献
Murty; Ramalingam; Sabitha; Yadav
Heterocyclic Communications, 2001 , vol. 7, # 5 p. 449 - 454
反应条件
1: 82 percent / N-bromosuccinimide; benzoylperoxide / CCl4 / 2 h / Heating 2: 80 percent / 5 h / 150 °C 3: 80 percent / potassium hydroxide / tetrahydrofuran / 0.25 h / 20 °C 4: 80 percent / aq. sodium hydroxide; hydrogen / Pd/C / 12 h / 100 °C / 15200 Torr 5: 60 percent / polyphosphoric acid / xylene / 2 h / 120 - 130 °C View Scheme
参考文献
Heterocyclic Communications, , vol. 7, # 5 p. 449 - 454
反应条件
methanesulfonic acid T=110°C; 2 h;
参考文献
Bollinger; Cooper; Gubler; Leutwiler; Payne
Helvetica Chimica Acta, 1990 , vol. 73, # 5 p. 1197 - 1204
反应条件
1: 45 percent / sodium hydride / dimethylformamide / 12 h / 20 °C 2: 80 percent / aq. sodium hydroxide; hydrogen / Pd/C / 12 h / 100 °C / 15200 Torr 3: 60 percent / polyphosphoric acid / xylene / 2 h / 120 - 130 °C View Scheme
参考文献
Heterocyclic Communications, , vol. 7, # 5 p. 449 - 454
反应条件
1: 80 percent / 5 h / 150 °C 2: 80 percent / potassium hydroxide / tetrahydrofuran / 0.25 h / 20 °C 3: 80 percent / aq. sodium hydroxide; hydrogen / Pd/C / 12 h / 100 °C / 15200 Torr 4: 60 percent / polyphosphoric acid / xylene / 2 h / 120 - 130 °C View Scheme
参考文献
Heterocyclic Communications, , vol. 7, # 5 p. 449 - 454
反应条件
1: 80 percent / aq. sodium hydroxide; hydrogen / Pd/C / 12 h / 100 °C / 15200 Torr 2: 60 percent / polyphosphoric acid / xylene / 2 h / 120 - 130 °C View Scheme
参考文献
Heterocyclic Communications, , vol. 7, # 5 p. 449 - 454
反应条件
1: 80 percent / potassium hydroxide / tetrahydrofuran / 0.25 h / 20 °C 2: 80 percent / aq. sodium hydroxide; hydrogen / Pd/C / 12 h / 100 °C / 15200 Torr 3: 60 percent / polyphosphoric acid / xylene / 2 h / 120 - 130 °C View Scheme
参考文献
Heterocyclic Communications, , vol. 7, # 5 p. 449 - 454
反应条件
2: 33 percent / MeSO3H / 2 h / 110 °C View Scheme
参考文献
Helvetica Chimica Acta, , vol. 73, # 5 p. 1197 - 1204
反应条件
2: 33 percent / MeSO3H / 2 h / 110 °C View Scheme
参考文献
Helvetica Chimica Acta, , vol. 73, # 5 p. 1197 - 1204
反应条件
1: N-bromosuccinimide, dibenzyl peroxide / CCl4 / 3 h / Heating; alkaline mother methanolic liquor after XXII was diluted with water and extracted dichlormethane 2: mother liquors after XXIV diluted warwe and extracted with dichlormethane View Scheme
参考文献
Polivka, Zdenek; Budesinsky, Milos; Holubek, Jiri; Schneider, Bohdan; Sediva, Zdenek; et al.
Collection of Czechoslovak Chemical Communications, 1989 , vol. 54, # 9 p. 2443 - 2469
