ammonia in methanol 18 h; Ambient temperature;

1: N,O-bis(trimethylsilyl)acetamide; trimethylsilyl triflate / acetonitrile / 0.08 h / 130 °C / microwave irradiation 2: NH3 / methanol / 16 h / 50 °C View Scheme

1: N,O-bis(trimethylsilyl)acetamide; trimethylsilyl triflate / acetonitrile / 0.08 h / 130 °C / microwave irradiation 2: NH3 / methanol / 16 h / 50 °C View Scheme

1: 1) 1,1,1,3,3,3-hexamethyldisilazane, (NH4)2SO4, pyridine, 2) TMS-triflate / 1) 3 h, reflux, 2) 1,2-dichloroethane, 6 h, r.t. 2: 88 percent / NH3 / methanol / 18 h / Ambient temperature View Scheme