sodium hydroxide T=40°C;

1.1: 80 percent / ammonium persulfate / ethanol / 12 h / Heating 2.1: 88 percent / magnesium monoperoxyphthalate / ethanol; H2O / 1 h / 50 °C 3.1: sodium hydride / tetrahydrofuran / 3 h / Heating 3.2: 34 percent / tetrahydrofuran / 12 h / 20 °C 4.1: 42 percent / acetonitrile / 1 h / Heating View Scheme

1.1: sodium hydride / tetrahydrofuran / 3 h / Heating 1.2: 51 percent / tetrahydrofuran / 18 h / 20 °C 2.1: 42 percent / acetonitrile / 1 h / Heating View Scheme

in methanol T=25°C;

1: 72 percent / HCl / acetone / 0.17 h / Heating 2: acetonitrile / 2 h / Heating View Scheme

in acetonitrile Substitution; 1 h; Heating;