甲基2-(2-甲酰基苯基)苯甲酸酯合成路线 （共 16 条）
反应条件
1: (i) nBuLi, (ii) /BRN= 1877728/ 2: (i) LiAlH4, (ii) Py*HClCrO3 3: ethanol / 4 h / Ambient temperature 4: H2 / Pd-C 5: (i) H2, Pd-C, (ii) Py*HClCrO3 View Scheme
参考文献
Padwa,A. et al.
Journal of Organic Chemistry, 1978 , vol. 43, # 3 p. 381 - 387
反应条件
1: With water; lithium hydroxide hydrate in tetrahydrofuran T=40°C; 2: With hydrogenchloride in tetrahydrofuran; water pH=7;
参考文献
Mehta, Vaibhav P.; Modha, Sachin G.; Ruijter, Eelco; Van Hecke, Kristof; Van Meervelt, Luc; Pannecouque, Christophe; Balzarini, Jan; Orru, Romano V. A.; Van Der Eycken, Erik
Journal of Organic Chemistry, 2011 , vol. 76, # 8 p. 2828 - 2839
反应条件
palladium diacetate; triphenylphosphine; cesium fluoride in N,N-dimethyl-formamide
T=100°C; Suzuki-Miyaura coupling; 72 h;
参考文献
Knowles, Jonathan P.; O'Connor, Victoria E.; Whiting, Andrew
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 6 p. 1876 - 1886
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in 1,4-dioxane; water
T=120°C; Suzuki-Miyaura cross-coupling; 0.416667 h; SealedIrradiation;
参考文献
Mehta, Vaibhav P.; Modha, Sachin G.; Ruijter, Eelco; Van Hecke, Kristof; Van Meervelt, Luc; Pannecouque, Christophe; Balzarini, Jan; Orru, Romano V. A.; Van Der Eycken, Erik
Journal of Organic Chemistry, 2011 , vol. 76, # 8 p. 2828 - 2839
反应条件
1: O3 / 0 °C
2: methanol / 6 h / Ambient temperature
View Scheme
参考文献
Neumeister, Joachim; Griesbaum, Karl
Chemische Berichte, 1984 , vol. 117, # 4 p. 1640 - 1642
反应条件
1: sulfuric acid / Reflux
2: palladium diacetate; triphenylphosphine; cesium fluoride / N,N-dimethyl-formamide / 72 h / 100 °C
View Scheme
参考文献
Knowles, Jonathan P.; O'Connor, Victoria E.; Whiting, Andrew
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 6 p. 1876 - 1886
参考文献
Bailey
Journal of the American Chemical Society, 1956 , vol. 78, p. 3811,3815
反应条件
in methanol
6 h; Ambient temperature;
参考文献
Neumeister, Joachim; Griesbaum, Karl
Chemische Berichte, 1984 , vol. 117, # 4 p. 1640 - 1642
反应条件
Yield given. Multistep reaction;
参考文献
Blettner, Carsten G.; Koenig, Wilfried A.; Stenzel, Wolfgang; Schotten, Theo
Synlett, 1998 , # 3 p. 295 - 297
反应条件
hydrogenchloride
Heating; Product distribution;
参考文献
Griesbaum, Karl; Neumeister, Joachim
Chemische Berichte, 1982 , vol. 115, # 8 p. 2697 - 2706
