1: NaH / tetrahydrofuran / 1.) r.t., 30 min, 2.) 0 deg C, 45 min View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1361988', constants.ctx, '0')">oxalyl dichloride</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '506008', constants.ctx, '0')">dimethyl sulfoxide</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '605283', constants.ctx, '0')">triethylamine</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a> <br />T=-78&deg;C;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 2 h / 120 &deg;C<br />2: 1.) borane methyl sulfide, 2.) 3 N aq. NaOH, 30percent aq. H₂O₂ / 1.) THF, 0 deg C, 2 h; r.t., 2.5 h, 2.) EtOH, 0 deg C, 30 min; r.t., 2 h<br />3: 1.) DMSO, oxalyl chloride, 2.) Et₃N / 1.) CH₂Cl₂, -78 deg C, 15 min, 2.) -78 deg C, 45 min<br /> <br /> &nbsp;