1-N-Cbz-哌啶-4-氧基乙酸合成路线 （共 5 条）
反应条件
trifluoroacetic acid in dichloromethane T=0 - 20°C;
参考文献
Song, Xiaoping; Xu, Christine R.; He, Henry T.; Siahaan, Teruna J.
Bioorganic Chemistry, 2002 , vol. 30, # 4 p. 285 - 301
反应条件
1: With water; sodium hydroxide in methanol 3 h; Heating / reflux; 2: With hydrogenchloride in water T=20°C; pH=3;
参考文献
Dainippon Sumitomo Pharma Co., Ltd.
Patent: WO2007/37518 A1, 2007 ;
Location in patent: Page/Page column 94 ;
反应条件
1: 96 percent / triethylamine / CH2Cl2 / 17 h / 0 - 25 °C 2: 90 percent / tetra-n-butylammonium hydrogen sulfate; NaOH / toluene; H2O / 20 h 3: 100 percent / trifluoroacetic acid / CH2Cl2 / 0 - 20 °C View Scheme
参考文献
Song, Xiaoping; Xu, Christine R.; He, Henry T.; Siahaan, Teruna J.
Bioorganic Chemistry, 2002 , vol. 30, # 4 p. 285 - 301
反应条件
1: 90 percent / tetra-n-butylammonium hydrogen sulfate; NaOH / toluene; H2O / 20 h 2: 100 percent / trifluoroacetic acid / CH2Cl2 / 0 - 20 °C View Scheme
参考文献
Song, Xiaoping; Xu, Christine R.; He, Henry T.; Siahaan, Teruna J.
Bioorganic Chemistry, 2002 , vol. 30, # 4 p. 285 - 301
反应条件
1: 96 percent / triethylamine / CH2Cl2 / 17 h / 0 - 25 °C 2: 90 percent / tetra-n-butylammonium hydrogen sulfate; NaOH / toluene; H2O / 20 h 3: 100 percent / trifluoroacetic acid / CH2Cl2 / 0 - 20 °C View Scheme
参考文献
Song, Xiaoping; Xu, Christine R.; He, Henry T.; Siahaan, Teruna J.
Bioorganic Chemistry, 2002 , vol. 30, # 4 p. 285 - 301
