(4S,5R)-(-)-4-甲基-5-苯基-2-噁唑烷酮合成路线 (共 28 条)
反应条件
potassium hydroxide in tetrahydrofuran; methanol 3 h; Ambient temperature;
参考文献
Kano, Shinzo; Yokomatsu, Tsutomu; Iwasawa, Haruo; Shibuya, Shiroshi
Tetrahedron Letters, 1987 , vol. 28, # 50 p. 6331 - 6334
反应条件
1: NaBH4 / methanol / 0.5 h / 20 - 25 °C 2: KOH / methanol; H2O / 35 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 103, # 20 p. 6157 - 6163
反应条件
potassium carbonate T=130°C; 1 h;
参考文献
Jeong, Eun Jeong; Kang, Eun Joo; Sung, Lee Taek; Hong, Sung Kil; Lee, Eun
Journal of the American Chemical Society, 2002 , vol. 124, # 49 p. 14655 - 14662
反应条件
lithium diisopropyl amide in tetrahydrofuran 1.) -78 deg C, 20 min, 2.) -78 deg C, 2 h; -78 to 20 deg C;
参考文献
Arvanitis, Elena; Ernst, Holger; Ludwig, Alice A.; Robinson, Andrew J.; Wyatt, Peter B.
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 3 p. 521 - 528
反应条件
(+/-)-2-Ethyloxirane; trifluoroacetic acid in dichloromethane T=0°C;
参考文献
Calo, Vinzenzo; Nacci, Angelo; Volpe, Angela
Gazzetta Chimica Italiana, 1997 , vol. 127, # 5 p. 283 - 286
参考文献
Cutugno, Sara; Martelli, Gianluca; Negro, Lucia; Savoia, Diego
European Journal of Organic Chemistry, 2001 , # 3 p. 517 - 522
反应条件
1.1: 67 percent / Bu2BOTf; diisopropylethylamine / diethyl ether / 2 h / -78 °C 2.1: trimethylaluminum / tetrahydrofuran; toluene / 0 - 20 °C 2.2: 450 mg / tetrahydrofuran; toluene / 1.5 h / 50 °C View Scheme
参考文献
Tetrahedron, , vol. 60, # 38 p. 8509 - 8527
反应条件
molecule imprinted polymer in acetonitrile T=25°C; pH=7; Resolution of racemateaq. phosphate buffer;
参考文献
Bulletin of the Korean Chemical Society, , vol. 33, # 5 p. 1664 - 1668
反应条件
lithium borohydride in tetrahydrofuran T=20°C; 2 h;
参考文献
Kinoshita, Hironori; Osamura, Takashi; Mizuno, Kazumi; Kinoshita, Sayaka; Iwamura, Tatsunori; Watanabe, Shin-Ichi; Kataoka, Tadashi; Muraoka, Osamu; Tanabe, Genzoh
Chemistry - A European Journal, 2006 , vol. 12, # 14 p. 3896 - 3904
反应条件
n-butyllithium in tetrahydrofuran T=0°C; 0.333333 h;
参考文献
Chemistry - A European Journal, , vol. 12, # 14 p. 3896 - 3904