N-Fmoc-N'-Boc-L-2,3-二氨基丙酸合成路线 （共 13 条）
反应条件
lithium hydroxide in tetrahydrofuran T=20°C;
参考文献
Rao, R. V. Ramana; Tantry, Subramanyam J.; Babu, Vommina V. Suresh
Synthetic Communications, 2006 , vol. 36, # 19 p. 2901 - 2912
反应条件
1: 94 percent / Na2CO3 / dioxane; H2O / 1 h / 20 °C 2: H2 / Pd/C / methanol 3: Et3N / tetrahydrofuran View Scheme
参考文献
Organic Letters, , vol. 8, # 22 p. 5009 - 5012
反应条件
1: H2 / Pd/C / methanol 2: Et3N / tetrahydrofuran View Scheme
参考文献
Organic Letters, , vol. 8, # 22 p. 5009 - 5012
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran; N,N-dimethyl-formamide 6 h; Ambient temperature;
参考文献
Hirschmann, Ralph; Yao, Wenqing; Arison, Byron; Maechler, Laurie; Rosegay, Avery; Sprengeler, Paul A.; Smith III, Amos B.
Tetrahedron, 1998 , vol. 54, # 25 p. 7179 - 7202
反应条件
sodium hydrogencarbonate in water; acetonitrile 6 h;
参考文献
Thurieau; Janiak; Krantic; Guyard; Pillon; Kucharczyk; Vilaine; Fauchere
European Journal of Medicinal Chemistry, 1995 , vol. 30, # 2 p. 115 - 122
反应条件
sodium carbonate in tetrahydrofuran
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 13 p. 2410 - 2417
反应条件
1.1: bis[trifluoroacetoxy]-phenyliodine / dimethylformamide; H2O / 0.25 h 1.2: 81 percent / pyridine / dimethylformamide; H2O / 10 h 2.1: DIEA / dimethylformamide / 4 h / 25 °C View Scheme
参考文献
Tetrahedron, , vol. 57, # 9 p. 1749 - 1755
反应条件
sodium carbonate in 1,4-dioxane; water Substitution;
参考文献
Zhang, Zhenyu; Aerschot, Arthur Van; Hendrix, Chris; Busson, Roger; David, Frank; Sandra, Pat; Herdewijn, Piet
Tetrahedron, 2000 , vol. 56, # 16 p. 2513 - 2522
反应条件
1: 87 percent / toluene / 0.25 h / microwave irradiation 2: 70 percent / LiOH / tetrahydrofuran / 20 °C View Scheme
参考文献
Synthetic Communications, , vol. 36, # 19 p. 2901 - 2912
反应条件
1: p-TsOH / toluene 2: 94 percent / N-methylmorpholine; IBC-Cl; NaN3 / tetrahydrofuran / 0.5 h / -10 °C 3: 87 percent / toluene / 0.25 h / microwave irradiation 4: 70 percent / LiOH / tetrahydrofuran / 20 °C View Scheme
参考文献
Synthetic Communications, , vol. 36, # 19 p. 2901 - 2912
