N-Fmoc-N'-Boc-L-2,3-二氨基丙酸合成路线 （共 13 条）
反应条件
1: 94 percent / N-methylmorpholine; IBC-Cl; NaN3 / tetrahydrofuran / 0.5 h / -10 °C 2: 87 percent / toluene / 0.25 h / microwave irradiation 3: 70 percent / LiOH / tetrahydrofuran / 20 °C View Scheme
参考文献
Synthetic Communications, , vol. 36, # 19 p. 2901 - 2912
反应条件
1.1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 0.17 h / 0 °C / Inert atmosphere 1.2: 18 h / 20 °C / Inert atmosphere 2.1: diethylamine / methanol / 3 h / 20 °C / Inert atmosphere View Scheme
参考文献
Advanced Synthesis and Catalysis, , vol. 352, # 18 p. 3153 - 3157
反应条件
trifluoroacetic acid in dichloromethane 1 h;
参考文献
Tulla-Puche, Judit; Auriemma, Sara; Falciani, Chiara; Albericio, Fernando
Journal of Medicinal Chemistry, 2013 , vol. 56, # 13 p. 5587 - 5600
