3-氧代-7alpha,12alpha-二羟基-5alpha-胆烷酸合成路线 (共 4 条)
反应条件
1: H+ 2: 88 percent / K-Selectride / tetrahydrofuran / 3 h / -20 °C 3: 100 percent / methanolic KOH View Scheme
参考文献
Iida; Nishida; Chang; Niwa; Goto; Nambara
Chemical and Pharmaceutical Bulletin, 1993 , vol. 41, # 4 p. 763 - 765
反应条件
hydrogen cation Yield given;
参考文献
Iida; Nishida; Chang; Niwa; Goto; Nambara
Chemical and Pharmaceutical Bulletin, 1993 , vol. 41, # 4 p. 763 - 765
反应条件
1: H+ 2: 88 percent / K-Selectride / tetrahydrofuran / 3 h / -20 °C 3: 100 percent / methanolic KOH View Scheme
参考文献
Iida; Nishida; Chang; Niwa; Goto; Nambara
Chemical and Pharmaceutical Bulletin, 1993 , vol. 41, # 4 p. 763 - 765
反应条件
Multi-step reaction with 2 steps 1: 87 percent / 2 M LiOH / methanol / 1.5 h / Ambient temperature2: lithium, liq. ammonia / tetrahydrofuran / 0.33 h / Ambient temperature
参考文献
Iida; Nishida; Chang; Niwa; Goto; Nambara Chemical and Pharmaceutical Bulletin, 1993 , vol. 41, # 4 p. 763 - 765