(Z)-3, 4, 5, 4’-四甲氧基-3’-氨基二苯乙烯合成路线 （共 14 条）
反应条件
sodium methylate in methanol; toluene
T=5 - 13°C; Wittig Reaction; Product distribution / selectivity;
参考文献
AVENTIS PHARMA SA
Patent: JP2005/522478 A, 2005 ;
Location in patent: Page/Page column 14 ;
反应条件
sodium methylate in methanol; toluene
T=5 - 14°C; Wittig Reaction; 2.75 h; Product distribution / selectivity;
参考文献
AVENTIS PHARMA SA
Patent: JP2005/522478 A, 2005 ;
Location in patent: Page/Page column 16-17 ;
反应条件
1: acetic anhydride; triethylamine / 3 h / 140 °C
2: copper; quinoline / 2 h / 140 °C
3: acetic acid; zinc / 24 h / 20 °C
View Scheme
参考文献
Liu, Ying-Qian; Li, Xiao-Jing; Zhao, Chun-Yan; Nan, Xiang; Tian, Jing; Morris-Natschke, Susan L.; Zhang, Zhi-Jun; Yang, Xiao-Ming; Yang, Liu; Li, Lin-Hai; Zhou, Xing-Wen; Lee, Kuo-Hsiung
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 5 p. 1248 - 1256
反应条件
1: copper; quinoline / 2 h / 140 °C
2: acetic acid; zinc / 24 h / 20 °C
View Scheme
参考文献
Liu, Ying-Qian; Li, Xiao-Jing; Zhao, Chun-Yan; Nan, Xiang; Tian, Jing; Morris-Natschke, Susan L.; Zhang, Zhi-Jun; Yang, Xiao-Ming; Yang, Liu; Li, Lin-Hai; Zhou, Xing-Wen; Lee, Kuo-Hsiung
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 5 p. 1248 - 1256
