3-(2-甲氧基苯氧基)-1-哌嗪-2-丙醇合成路线 （共 3 条）
反应条件
in ethanol T=65°C; 1.5 h;
参考文献
Yao, Zhangyu; Gong, Shubo; Guan, Teng; Li, Yunman; Wu, Xiaoming; Sun, Hongbin
Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 11 p. 1218 - 1222
反应条件
1: sodium hydroxide / 1,4-dioxane; water / 3 h / Reflux 2: methanol / 3 h / 0 - 5 °C View Scheme
参考文献
Madivada, Lokeswara Rao; Anumala, Raghupathi Reddy; Gilla, Goverdhan; Kagga, Mukkanti; Bandichhor, Rakeshwar
Organic Process Research and Development, 2012 , vol. 16, # 10 p. 1660 - 1664
反应条件
potassium carbonate; sodium iodide in N,N-dimethyl-formamide T=30 - 35°C; 18 h;
参考文献
AUSPEX PHARMACEUTICALS, INC.
Patent: US2008/312247 A1, 2008 ;
Location in patent: Page/Page column 31-32 ;
