2,4-二溴-1-甲基-5-硝基-1H-咪唑合成路线 （共 4 条）
反应条件
in tetrahydrofuran T=20°C; Methylation; 1 h;
参考文献
Journal of Heterocyclic Chemistry, , vol. 37, # 1 p. 119 - 126
反应条件
in diethyl ether T=20°C; 1 h;
参考文献
Chauviere, Gerard; Bouteille, Bernard; Enanga, Bertin; De Albuquerque, Cristina; Croft, Simon L.; Dumas, Michel; Perie, Jacques
Journal of Medicinal Chemistry, 2003 , vol. 46, # 3 p. 427 - 440
反应条件
18-crown-6 ether in dimethyl sulfoxide T=80°C; Substitution; 2 h;
参考文献
Chauviere, Gerard; Bouteille, Bernard; Enanga, Bertin; De Albuquerque, Cristina; Croft, Simon L.; Dumas, Michel; Perie, Jacques
Journal of Medicinal Chemistry, 2003 , vol. 46, # 3 p. 427 - 440
反应条件
sodium tetrahydroborate in water; dimethyl sulfoxide
T=80°C; Reduction; 1 h;
参考文献
Chauviere, Gerard; Viode, Cecile; Perie, Jacques
Journal of Heterocyclic Chemistry, 2000 , vol. 37, # 1 p. 119 - 126
