5-(噻吩-2-基)噻吩-2-甲腈合成路线 （共 9 条）
反应条件
1: 85 percent / Pd(PPh3)4 / dioxane / 24 h / 80 - 90 °C 2: aq. NH2OH*HCl; Na2CO3 / methanol / 6 h / Heating 3: Ac2O / 4 h / Heating View Scheme
参考文献
Journal of Chemical Research, , # 11 p. 733 - 737
反应条件
1: N-bromosuccinmide / N,N-dimethyl-formamide 2: dimethyl sulfoxide View Scheme
参考文献
Physical Chemistry Chemical Physics, , vol. 13, # 7 p. 2690 - 2700
反应条件
1: aq. NH2OH*HCl; Na2CO3 / methanol / 6 h / Heating 2: Ac2O / 4 h / Heating View Scheme
参考文献
Journal of Chemical Research, , # 11 p. 733 - 737
反应条件
n-butyllithium 1.) THF, 0 deg C, 30 min, 2.) THF, -78 deg C, 1 h; room temperature, 1 h; Yield givenMultistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 64, # 1 p. 313 - 315
反应条件
n-butyllithium 1.) THF, 0 deg C, 30 min, 2.) THF, -78 deg C; Yield givenMultistep reaction. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 64, # 1 p. 313 - 315
反应条件
in dimethyl sulfoxide
参考文献
Physical Chemistry Chemical Physics, , vol. 13, # 7 p. 2690 - 2700
反应条件
acetic anhydride 4 h; Heating;
参考文献
Journal of Chemical Research, , # 11 p. 733 - 737
反应条件
n-butyllithium multistep reaction: 1.) THF, 0 deg C, 30 min, 2.) THF, -78 deg C, 1 h; room temperarure, 1 h; electrophilic cyanation of arenes, heteroarenes and alkynes using 1-cyanobenzotriazole; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 64, # 1 p. 313 - 315
反应条件
1: sulfur; hydrazine / ethanol
2: oxydation
View Scheme
参考文献
Kurach, Ewa; Djurado, David; Rimarik, Jan; Kornet, Aleksandra; Wlostowski, Marek; Luke, Vladimir; Pecaut, Jacques; Zagorska, Malgorzata; Pron, Adam
Physical Chemistry Chemical Physics, 2011 , vol. 13, # 7 p. 2690 - 2700
