反应条件
1: 1.) LDA / 1.) THF, hexane, -60 deg C, 90 min, 2.) a) 3 min, b) RT, 2 h 2: 85 percent / NaH / methanol / 3 h / Heating 3: 91 percent / p-toluenesulfonic acid / benzene / 3 h / Heating 4: 1.) n-BuLi / 1.) ether, hexane, RT, 15 min, 2.) 22 deg C, 1 h 5: 72 percent / H2, potassium carbonate / Lindlar catalyst / toluene / 3 h / 20 °C / 760 Torr 6: PBr3 / diethyl ether / 0.08 h / Ambient temperature 7: 69 percent / benzene / Heating 8: 78 percent / NaOCH3 / CH2Cl2; methanol / 1 h / -10 °C View Scheme
参考文献
Rosenberger; McDougal; Bahr
Journal of Organic Chemistry, 1982 , vol. 47, # 11 p. 2130 - 2134
