3-甲氧基-4-硝基苯酚合成路线 （共 14 条）
反应条件
1: With water; sodium hydroxide in dimethyl sulfoxide T=80°C; 20 h; 2: With hydrogenchloride in water; dimethyl sulfoxide T=20°C; pH=5;
参考文献
Bartkovitz, David Joseph; Chu, Xin-Jie; Ding, Qingjie; Karnachi, Prabha Saba; Liu, Jin-Jun; So, Sung-Sau; Zhang, Jing; Zhang, Zhuming
Patent: US2012/46306 A1, 2012 ;
Location in patent: Page/Page column 36 ;
反应条件
potassium carbonate in methanol 168 h; Reflux;
参考文献
CELLZOME LIMITED; RAMSDEN, Nigel; MAJOR, Jeremy; MOREL, Adeline; SUNOSE, Mihiro; PITON, Nelly
Patent: WO2010/142766 A2, 2010 ;
Location in patent: Page/Page column 43-44 ;
WO 2010/142766 A2
反应条件
1: With sodium 24 h; Reflux; 2: With hydrogenchloride; water in ethyl acetate pH=1;
参考文献
WO2009/144632 A1, ;
Page/Page column 77 ;
反应条件
alpha,alpha-dimethylbenzyl hydroperoxide; potassium tert-butylate in ammonia T=-33°C; 1 h;
参考文献
Makosza, Mieczyslaw; Sienkiewicz, Krzysztof
Journal of Organic Chemistry, 1998 , vol. 63, # 13 p. 4199 - 4208
反应条件
in tetrahydrofuran; methanol 18 h; Heating / reflux;
参考文献
WO2004/80980 A1, ;
Page 135 ;
WO 2004/080980 A1
参考文献
Bulletin de la Societe Chimique de France, , p. 4061 - 4067
反应条件
1: potassium carbonate / acetone / 3 h / |Reflux 2: sodium hydroxide / dimethyl sulfoxide / 21 h / 20 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 68, p. 233 - 243
反应条件
nitric acid; acetic acid
参考文献
Journal of the Chemical Society, , p. 2778
反应条件
1: permanganate 2: 160 - 170 °C / im Rohr View Scheme
参考文献
Journal of the Chemical Society, , p. 558
反应条件
1: glacial acetic acid; nitric acid 2: alcoholic KOH-solution 3: 160 - 170 °C / im Rohr View Scheme
参考文献
Journal of the Chemical Society, , p. 558
