(S)-(-)-2-(Boc-氨基)-1,5-戊二醇合成路线 （共 13 条）
反应条件
lithium borohydride in tetrahydrofuran T=0 - 20°C; Inert atmosphere;
参考文献
Suhartono, Marcel; Schneider, Angelika E.; Duerner, Gerd; Goebel, Michael W.
Synthesis, 2010 , # 2 art. no. T12409SS, p. 293 - 303
反应条件
Cp*RuCl{(C6H5)2P-(CH2)2NH2-κ2-P,N}; potassium tert-butylate; hydrogen in tert-butyl alcohol T=80°C; P=22502.3 Torr; 24 h; Autoclave;
参考文献
Angewandte Chemie - International Edition, , vol. 48, # 7 p. 1324 - 1327
反应条件
sodium tetrahydroborate in methanol; ethylene glycol dimethyl ether T=20°C; 36 h;
参考文献
Brena-Valle; Cruz-Almanza; Guadarrama-Morales
Synthetic Communications, 2001 , vol. 31, # 5 p. 697 - 706
反应条件
1: aq. NaOH / dioxane / 20 °C 2: diethyl ether / 0 °C 3: LiBH4 / tetrahydrofuran / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 42, # 43 p. 7599 - 7603
反应条件
1: aq. NaOH / dioxane / 20 °C 2: diethyl ether / 0 °C 3: LiBH4 / tetrahydrofuran / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 42, # 43 p. 7599 - 7603
反应条件
1: triethylamine / dichloromethane / 10.25 h / 0 - 20 °C / |Inert atmosphere 2: sodium tetrahydroborate; calcium chloride / ethanol / 4 h / |Inert atmosphere View Scheme
参考文献
Organic Letters, , vol. 14, # 17 p. 4518 - 4521
反应条件
sodium tetrahydroborate in ethanol Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 4 p. 495 - 505
反应条件
1: Et3N / dioxane; H2O / 2 h / 0 °C 2: NaBH4, CaCl2 / ethanol / 2 h / 0 °C View Scheme
参考文献
Synthetic Communications, , vol. 28, # 21 p. 3919 - 3926
反应条件
1: diethyl ether / 0 °C 2: LiBH4 / tetrahydrofuran / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 42, # 43 p. 7599 - 7603
反应条件
1: 68.7 percent / DMAP / acetonitrile / 24 h 2: 73.9 percent / NaBH4 / 1,2-dimethoxy-ethane; methanol / 36 h / 20 °C View Scheme
参考文献
Synthetic Communications, , vol. 31, # 5 p. 697 - 706
