5,5-二甲基-2,2-并噻吩合成路线 （共 31 条）
反应条件
tris(dibenzylideneacetone)dipalladium(0) chloroform complex; silver monofluoride in dimethyl sulfoxide T=60°C; 5 h;
参考文献
Masui, Kentaro; Ikegami, Haruka; Mori, Atsunori
Journal of the American Chemical Society, 2004 , vol. 126, # 16 p. 5074 - 5075
反应条件
1: With diethylzinc; 1-tert-butyl-4,4,4-tris(dimethylamino)-2,2-bis[tris(dimethylamino)-phosphoranylidenamino]-2Λ54Λ5-catenadi(phosphazene) in hexane; N,N-dimethyl acetamide T=20°C; 24 h; Inert atmosphere; 2: With chloranil in hexane; N,N-dimethyl acetamide T=20°C; 20 h; Inert atmosphere;
参考文献
Naka, Hiroshi; Ito, Keisuke; Ueno, Masahiro; Kobayashi, Koji; Kondo, Yoshinori
New Journal of Chemistry, 2010 , vol. 34, # 8 p. 1700 - 1706
反应条件
1: 2-bromo-5-methyl-thiophene With magnesium 2: 2-methyl-thiophene With [1,3-bis(diphenylphosphino) propane] dichloronickel(II)
参考文献
Marsella, Michael J.; Piao, Guangzhe; Tham, Fook S.
Synthesis, 2002 , # 9 p. 1133 - 1135
反应条件
[2,2']bipyridinyl; nickel diacetate; sodium tert-pentoxide in tetrahydrofuran T=25°C; 0.000416667 h;
参考文献
Forst, Yves; Becker, Sandrine; Caubere, Paul
Tetrahedron, 1994 , vol. 50, # 41 p. 11893 - 11902
反应条件
1: 2-(thien-2-yl)thiophene With n-butyllithium in tetrahydrofuran T=-15°C; 2 h; 2: methyl iodide in tetrahydrofuran 2 h; Heating; Further stages.;
参考文献
Bushnev
Petroleum Chemistry, 2007 , vol. 47, # 3 p. 184 - 192
反应条件
PdCl(C3H5)(dppb); caesium carbonate in N,N-dimethyl-formamide T=150°C; 20 h; Inert atmosphere; regioselective reaction;
参考文献
Derridj, Fazia; Gottumukkala, Aditya L.; Djebbar, Safia; Doucet, Henri
European Journal of Inorganic Chemistry, 2008 , # 16 p. 2550 - 2559
反应条件
tris-(dibenzylideneacetone)dipalladium(0); tetrabutyl ammonium fluoride in tetrahydrofuran; toluene T=100°C; 12 h; Inert atmosphere;
参考文献
Organic Letters, , vol. 12, # 4 p. 816 - 819
反应条件
PdCl(C3H5)(dppb); potassium acetate in N,N-dimethyl acetamide T=150°C; 20 h; Inert atmosphere; regioselective reaction;
参考文献
Derridj, Fazia; Gottumukkala, Aditya L.; Djebbar, Safia; Doucet, Henri
European Journal of Inorganic Chemistry, 2008 , # 16 p. 2550 - 2559
反应条件
PdCl(C3H5)(dppb); potassium acetate in N,N-dimethyl acetamide T=150°C; 20 h; Inert atmosphere; regioselective reaction;
参考文献
Derridj, Fazia; Gottumukkala, Aditya L.; Djebbar, Safia; Doucet, Henri
European Journal of Inorganic Chemistry, 2008 , # 16 p. 2550 - 2559
反应条件
tris-(dibenzylideneacetone)dipalladium(0); tetrabutyl ammonium fluoride in tetrahydrofuran; water; toluene T=100°C; 12 h; Inert atmosphere;
参考文献
Organic Letters, , vol. 12, # 4 p. 816 - 819
