5,5-二甲基-2,2-并噻吩合成路线 （共 31 条）
反应条件
tris-(dibenzylideneacetone)dipalladium(0); tetrabutyl ammonium fluoride; water in tetrahydrofuran; toluene T=100°C; 5 h; Inert atmosphere;
参考文献
Pitteloud, Jean-Philippe; Zhang, Zun-Ting; Liang, Yong; Cabrera, Laura; Wnuk, Stanislaw F.
Journal of Organic Chemistry, 2010 , vol. 75, # 23 p. 8199 - 8212
反应条件
tris-(dibenzylideneacetone)dipalladium(0); tetrabutyl ammonium fluoride; water in tetrahydrofuran; toluene T=100°C; 2 h; Inert atmosphere;
参考文献
Pitteloud, Jean-Philippe; Zhang, Zun-Ting; Liang, Yong; Cabrera, Laura; Wnuk, Stanislaw F.
Journal of Organic Chemistry, 2010 , vol. 75, # 23 p. 8199 - 8212
反应条件
silver hexafluoroantimonate; copper (II) 2-ethylhexanoate; [{(η5-C5Me5)RhCl}2(μ-Cl)2]; CsO2CCMe3 in 1,1-dimethylpropan-1-ol T=120°C; 20 h; Inert atmosphere;
参考文献
Angewandte Chemie - International Edition, , vol. 51, # 33 p. 8230 - 8234
反应条件
2-thienylmagnesium chloride in tetrahydrofuran T=0°C; 48 h;
参考文献
Journal of Organic Chemistry, , vol. 79, # 4 p. 1836 - 1841
反应条件
potassium hydroxide; hydrazine hydrate; diethylene glycol
参考文献
Journal of the Chemical Society, , p. 3234,3235
反应条件
oxygen 1.) 2-MeTHF, -125 deg C; 2.) -125 deg C; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 35, # 6 p. 815 - 818
反应条件
oxygen 1.) 2-MeTHF, -125 deg C; 2.) -125 deg C; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 35, # 6 p. 815 - 818
反应条件
1: dimethylformamide; phosphoryl chloride; toluene / anschliessendes Behandeln mit wss. Natriumacetat-Loesung 2: diethylene glycol; hydrazine hydrate; potassium hydroxide View Scheme
参考文献
Journal of the Chemical Society, , p. 3234,3235
反应条件
1: hydrazine hydrate; diethylene glycol; potassium hydroxide 2: dimethylformamide; phosphoryl chloride; toluene / anschliessendes Behandeln mit wss. Natriumacetat-Loesung 3: diethylene glycol; hydrazine hydrate; potassium hydroxide View Scheme
参考文献
Journal of the Chemical Society, , p. 3234,3235
反应条件
1: dimethylformamide; phosphoryl chloride; toluene / anschliessendes Behandeln mit wss. Natriumacetat-Loesung 2: hydrazine hydrate; diethylene glycol; potassium hydroxide 3: dimethylformamide; phosphoryl chloride; toluene / anschliessendes Behandeln mit wss. Natriumacetat-Loesung 4: diethylene glycol; hydrazine hydrate; potassium hydroxide View Scheme
参考文献
Journal of the Chemical Society, , p. 3234,3235
