1-[2-氯-6-[[(3-碘苯基)甲基]氨基]-9h-嘌呤-9-基]-1-脱氧-N-甲基-beta-d-呋喃核糖酰胺合成路线 (共 6 条)
反应条件
ammonia 16 h; Ambient temperature;
参考文献
Kim; Ji; Siddiqi; Olah; Stiles; Jacobson
Journal of Medicinal Chemistry, 1994 , vol. 37, # 21 p. 3614 - 3621
反应条件
1: 60 percent / Et3N / ethanol / 120 h / Ambient temperature 2: ammonium sulfate / 5 h / Heating 3: 33 percent / TMSOTf / 1,2-dichloro-ethane / 62 h / Heating 4: 68.7 percent / methanolic NH3 / 16 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 37, # 21 p. 3614 - 3621
反应条件
1: 60 percent / Et3N / ethanol / 120 h / Ambient temperature 2: ammonium sulfate / 5 h / Heating 3: 33 percent / TMSOTf / 1,2-dichloro-ethane / 62 h / Heating 4: 68.7 percent / methanolic NH3 / 16 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 37, # 21 p. 3614 - 3621
反应条件
1: ammonium sulfate / 5 h / Heating 2: 33 percent / TMSOTf / 1,2-dichloro-ethane / 62 h / Heating 3: 68.7 percent / methanolic NH3 / 16 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 37, # 21 p. 3614 - 3621
反应条件
1: 33 percent / TMSOTf / 1,2-dichloro-ethane / 62 h / Heating 2: 68.7 percent / methanolic NH3 / 16 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 37, # 21 p. 3614 - 3621
参考文献
US2005/256143 A1, ;
Page/Page column Sheet 1 of 3 ;