1: 1.) lithium 4,4'-di-tert-butylbiphenylide, 2.) CuBr*Me2S / 1.) THF, 30 min, 2.) THF, -78 deg C, 3 h, 3.) THF, -78 deg C, 12 h 2: 1.) p-toluenesulfonic acid, 2.) 5percent KOH, 40percent n-Bu4NOH / 1.) acetone, water, reflux 7 h, 2.) THF, water, reflux, 14 h View Scheme

1: 1.) lithium 4,4'-di-tert-butylbiphenylide, 2.) CuBr*Me2S / 1.) THF, 30 min, 2.) THF, -78 deg C, 3 h, 3.) THF, -78 deg C, 12 h 2: 1.) p-toluenesulfonic acid, 2.) 5percent KOH, 40percent n-Bu4NOH / 1.) acetone, water, reflux 7 h, 2.) THF, water, reflux, 14 h View Scheme