2-甲氧基-5-吡啶硼酸合成路线 （共 15 条）
反应条件
caesium carbonate in water
T=100°C; Suzuki coupling; 0.166667 h; Microwave irradiation;
参考文献
Worm-Leonhard, Kasper; Meldal, Morten
European Journal of Organic Chemistry, 2008 , # 31 p. 5244 - 5253
反应条件
caesium carbonate in water
T=90°C; Suzuki coupling; 0.166667 h; Microwave irradiation;
参考文献
Worm-Leonhard, Kasper; Meldal, Morten
European Journal of Organic Chemistry, 2008 , # 31 p. 5244 - 5253
反应条件
1: potassium carbonate; palladium diacetate; triphenylphosphine / water; ethylene glycol dimethyl ether / 5.67 h / |Reflux
2: hydrogenchloride / water / 3 h / |Reflux
3: copper diacetate; pyridine / N,N-dimethyl-formamide / 20 °C
4: N-bromosuccinmide / N,N-dimethyl-formamide / 2.5 h / 20 °C
View Scheme
参考文献
Hibi, Shigeki; Ueno, Koshi; Nagato, Satoshi; Kawano, Koki; Ito, Koichi; Norimine, Yoshihiko; Takenaka, Osamu; Hanada, Takahisa; Yonaga, Masahiro
Journal of Medicinal Chemistry, 2012 , vol. 55, # 23 p. 10584 - 10600
反应条件
palladium diacetate; potassium carbonate; triphenylphosphine in ethylene glycol dimethyl ether; water
Suzuki-Miyaura Coupling; 5.66667 h; Reflux;
参考文献
Hibi, Shigeki; Ueno, Koshi; Nagato, Satoshi; Kawano, Koki; Ito, Koichi; Norimine, Yoshihiko; Takenaka, Osamu; Hanada, Takahisa; Yonaga, Masahiro
Journal of Medicinal Chemistry, 2012 , vol. 55, # 23 p. 10584 - 10600
反应条件
ammonium hydroxide; ammonium chloride; potassium carbonate; triphenylphosphine; palladium diacetate in water; ethyl acetate
参考文献
Eisai Co., Ltd.
Patent: EP1300396 A1, 2003 ;
