2-氨基-5-硝基苯酰胺合成路线 （共 16 条）
反应条件
ammonia; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in water; N,N-dimethyl-formamide T=20°C; 1 h;
参考文献
Tobe, Masanori; Isobe, Yoshiaki; Tomizawa, Hideyuki; Nagasaki, Takahiro; Takahashi, Hirotada; Fukazawa, Tominaga; Hayashi, Hideya
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 3 p. 383 - 391
反应条件
sulfuric acid T=130°C; 0.333333 h;
参考文献
Lessel
Archiv der Pharmazie, 1994 , vol. 327, # 9 p. 571 - 579
反应条件
ammonia T=150°C; im Druckrohr;
参考文献
Chemische Berichte, , vol. 24, p. 3814
反应条件
sodium azide; sulfuric acid T=0°C;
参考文献
Journal of the Chemical Society, , p. 1713
反应条件
2: alcoholic ammonia / 150 °C / im Druckrohr View Scheme
参考文献
Chemische Berichte, , vol. 24, p. 3814
反应条件
1: PCl5 3: alcoholic ammonia / 150 °C / im Druckrohr View Scheme
参考文献
Chemische Berichte, , vol. 24, p. 3814
反应条件
hydrogenchloride T=20°C; 1.5 h;
参考文献
Tobe, Masanori; Isobe, Yoshiaki; Tomizawa, Hideyuki; Nagasaki, Takahiro; Takahashi, Hirotada; Fukazawa, Tominaga; Hayashi, Hideya
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 3 p. 383 - 391
反应条件
1: aq. HCl / 1 h 2: thionyl chloride; N,N-dimethylformamide / 3 h / Heating View Scheme
参考文献
Tobe, Masanori; Isobe, Yoshiaki; Tomizawa, Hideyuki; Matsumoto, Mitsuhiro; Obara, Fumihiro; Nagasaki, Takahiro; Hayashi, Hideya
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 4 p. 545 - 548
反应条件
1: aq. HCl / 1 h
2: thionyl chloride; N,N-dimethylformamide / 3 h / Heating
3: 373 mg / triethylamine / propan-2-ol / 2 h / 20 °C
View Scheme
参考文献
Tobe, Masanori; Isobe, Yoshiaki; Tomizawa, Hideyuki; Nagasaki, Takahiro; Takahashi, Hirotada; Hayashi, Hideya
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 18 p. 3869 - 3878
反应条件
1: aq. HCl / 1 h
2: thionyl chloride; N,N-dimethylformamide / 3 h / Heating
3: triethylamine / propan-2-ol / 20 °C
View Scheme
参考文献
Tobe, Masanori; Isobe, Yoshiaki; Tomizawa, Hideyuki; Nagasaki, Takahiro; Takahashi, Hirotada; Hayashi, Hideya
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 18 p. 3869 - 3878
