2',3',5'-三-O-乙酰-2-氨基-6-氯嘌呤核苷合成路线 （共 36 条）
反应条件
copper(l) iodide; diiodomethane; iodine; isopentyl nitrite in tetrahydrofuran 0.75 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 2 p. 241 - 252
反应条件
I2; CuI; iodine in tetrahydrofuran
参考文献
University of Virginia Patent Foundation
Patent: US6232297 B1, 2001 ;
US 6232297 B1
反应条件
copper(l) iodide; diiodomethane; iodine; isopentyl nitrite T=80°C; 0.25 h;
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 2 p. 241 - 252
反应条件
diiodomethane; isopentyl nitrite T=80°C; 0.416667 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 2 p. 241 - 252
反应条件
1: CH2I2, n-C5H11ONO / acetonitrile / 65 °C 2: NH3 / methanol / 0 - 25 °C View Scheme
参考文献
Nair; Turner; Buenger; Chamberlain
Journal of Organic Chemistry, 1988 , vol. 53, # 13 p. 3051 - 3057
反应条件
1: 75 percent / isoamyl nitrite, trimethylsilyl azide / acetonitrile / 1) -20 deg C, 12 h; 2) 0 deg C, 2 d 2: 89 percent / NH3 / ethanol / 48 h / 30 °C View Scheme
参考文献
Higashiya, Seiichiro; Kaibara, Chitose; Fukuoka, Koichiro; Suda, Fuminori; Ishikawa, Masahide; Yoshida, Masasuke; Hata, Tsujiaki
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 1 p. 39 - 42
反应条件
dichloro-acetic acid; sodium nitrite in tetrahydrofuran
参考文献
Francom, Paula; Janeba, Zlatko; Shibuya, Susumu; Robins, Morris J.
Journal of Organic Chemistry, 2002 , vol. 67, # 19 p. 6788 - 6796
反应条件
copper(l) iodide; diiodomethane; iodine; isopentyl nitrite in tetrahydrofuran 0.75 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 2 p. 241 - 252
反应条件
chloro-trimethyl-silane; tert.-butylnitrite; 1,1-dibromomethane T=20°C; 3 h;
参考文献
Journal of Organic Chemistry, , vol. 68, # 2 p. 666 - 669
参考文献
Volpini, Rosaria; Marucci, Gabriella; Buccioni, Michela; DalBen, Diego; Lambertucci, Catia; Lammi, Carmen; Mishra, Ram C.; Thomas, Ajiroghene; Cristalli, Gloria
ChemMedChem, 2011 , vol. 6, # 6 p. 1074 - 1080
