(S)-2-氨基-4-戊烯酸叔丁酯合成路线 (共 5 条)
反应条件
potassium hydroxide; hydrogen cation; N-anthracenyl methyl cinchonidium chloride 1.) PhMe, H2O, 18 h, RT; 2.) H2O; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Lygo; Crosby; Lowdon; Peterson; Wainwright
Tetrahedron, 2001 , vol. 57, # 12 p. 2403 - 2409
反应条件
1: With water; hydrogenchloride in tetrahydrofuran T=0°C; 0.5 h; 2: With sodium hydrogencarbonate in water T=0°C;
参考文献
NAGASE and CO., LTD.
Patent: WO2007/13698 A1, 2007 ;
Location in patent: Page/Page column 106-107 ;
反应条件
1: With water; citric acid in tetrahydrofuran T=20°C; 3 h; 2: With potassium carbonate in tetrahydrofuran; water
参考文献
Benohoud, Meryem; Leman, Loic; Cardoso, Silvia H.; Retailleau, Pascal; Dauban, Philippe; Thierry, Josiane; Dodd, Robert H.
Journal of Organic Chemistry, 2009 , vol. 74, # 15 p. 5331 - 5336
反应条件
hexacarbonyl molybdenum in water; acetonitrile
参考文献
Hanessian, Stephen; Yang, Rui-Yang
Tetrahedron Letters, 1996 , vol. 37, # 50 p. 8997 - 9000
参考文献
Hanessian, Stephen; Yang, Rui-Yang
Tetrahedron Letters, 1996 , vol. 37, # 50 p. 8997 - 9000