依泽替米贝合成路线

191330-56-0(3R,4S)-1-(4-氟苯基)-3-[3-(4-氟苯基)-3-氧代丙基]-4-(4-羟基苯基)氮杂环丁烷-2-酮

参考文献

TEVA PHARMACEUTICAL INDUSTRIES LTD.; TEVA PHARMACEUTICALS USA, INC.
Patent: WO2008/151324 A1, 2008 ;
Location in patent: Page/Page column 18 ;

163222-32-0(3R,4S)-1-(4-氟苯基)-3-[(3S)-3-(4-氟苯基)-3-羟基丙基]-4-[4-(苯甲氧基)苯基]-2-氮杂环丁酮

163222-33-1依泽替米贝

参考文献

Sniezek, Marcin; Stecko, Sebastian; Panfil, Irma; Furman, Bartlomiej; Chmielewski, Marek
Journal of Organic Chemistry, 2013 , vol. 78, # 14 p. 7048 - 7057

1197343-05-7

163222-33-1依泽替米贝

参考文献

WO2009/140932 A2, ;

Page/Page column 10-11 ;

1232148-26-3

163222-33-1依泽替米贝

参考文献

HANMI PHARM. CO., LTD.; KIM, Gi Jeong; KIM, Choong Hahn; CHANG, Ji Yeon; KIM, Nam Du; CHANG, Young Kil; LEE, Gwan Sun
Patent: WO2010/71358 A2, 2010 ;
Location in patent: Page/Page column 18-19 ;

191330-56-0(3R,4S)-1-(4-氟苯基)-3-[3-(4-氟苯基)-3-氧代丙基]-4-(4-羟基苯基)氮杂环丁烷-2-酮

163222-33-1依泽替米贝+

163380-16-3(3’R)-依折麦布

参考文献

US2006/69080 A1, ;

Page/Page column 27 ;

190595-65-4(3R,4S)-4-[4-(苄氧基)苯基]-1-(4-氟苯基)-3-[3-(4-氟苯基)-3-氧代丙基]氮杂环丁烷-2-酮

163222-33-1依泽替米贝+

163380-16-3(3’R)-依折麦布

参考文献

US2005/96307 A1, ;

Page/Page column 24 ;

1159183-24-0

163222-33-1依泽替米贝