1: 4-oxo-3,4-dihydroquinazoline With potassium tert-butylate in N,N-dimethyl-formamide T=20°C; 0.25 h; 2: propargyl bromide in N,N-dimethyl-formamide T=20°C; 0.25 h;

1: anthranilic acid; N,N-dimethyl-formamide dimethyl acetal in N,N-dimethyl-formamide T=100°C; P=760.051 Torr; 0.25 h; Microwave irradiationInert atmosphereGreen chemistry; 2: monopropargylamine With acetic acid T=100°C; P=760.051 Torr; 0.25 h; Inert atmosphereMicrowave irradiationGreen chemistry;

acetic acid in ethanol 4 h; Heating;

in 1,2-dichloro-benzene T=180°C; 12 h;

1: 1.) sodium / 2.) 2 h, reflux 2: 22 percent / 1,2-dichloro-benzene / 12 h / 180 °C View Scheme

1.1: 0.25 h / |Irradiation 2.1: potassium tert-butylate / N,N-dimethyl-formamide / 0.25 h / 20 °C 2.2: 0.25 h / 20 °C View Scheme

1: 89 percent / dimethylformamide / 3 h / 40 - 50 °C 2: 85 percent / HOAc / ethanol / 4 h / Heating View Scheme

1: thermolysis 2: 1.) sodium / 1.) methanol; 2.) methanol, room temperature View Scheme

1: KOtBu / 2-methyl-propan-2-ol / 80 °C 2: KOH / aq. ethanol 3: (i) HNO2, (ii) H3PO2 View Scheme