1: t-BuOK / dimethylformamide / 4 h / Ambient temperature 2: 30percent aq. H2O2 / dimethylformamide / 0 - 20 °C 3: H2 / Raney nickel / tetrahydrofuran / 12 h / 3102.9 Torr View Scheme
参考文献
Tebbe, Mark J.; Spitzer, Wayne A.; Victor, Frantz; Miller, Shawn C.; Lee, Chris C.; Sattelberg Sr., Thomas R.; McKinney, Emma; Tang, Joseph C.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 24 p. 3937 - 3946