(1R,4S)-2-氧代-7-氮杂双环[2.2.1]庚烷-7-羧酸叔丁酯合成路线 （共 72 条）
反应条件
Dess-Martin periodane in dichloromethane T=20°C;
参考文献
GEORGETOWN UNIVERSITY
Patent: WO2005/806 A2, 2005 ;
Location in patent: Page 71 ;
WO 2005/000806 A2
反应条件
hydrogen; palladium on activated charcoal in ethanol; ethyl acetate P=2844.31 Torr; 10 h;
参考文献
Pandey, Ganesh; Tiwari, Shashi Kant; Singh, Ram Shanker; Mali, Raghao S.
Tetrahedron Letters, 2001 , vol. 42, # 23 p. 3947 - 3949
反应条件
hydrogenchloride; triethylamine in dichloromethane
参考文献
NODE, MANABU; NAKAMURA, DAISAKU; FUJIWARA, TOSHIO; ICHIHASHI, SHOGO
Patent: US2002/10339 A1, 2002 ;
反应条件
oxalyl dichloride; dimethyl sulfoxide; triethylamine in dichloromethane T=-70 - 20°C;
参考文献
Albertini, Enrichetta; Barco, Achille; Benetti, Simonetta; De Risi, Carmela; Pollini, Gian P.; Zanirato, Vinicio
Tetrahedron, 1997 , vol. 53, # 50 p. 17177 - 17194
反应条件
hydrogen; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal in methanol 5 h;
参考文献
Campbell; Rapoport
Journal of Organic Chemistry, 1996 , vol. 61, # 18 p. 6313 - 6325
反应条件
dimethylsulfide; Sudan III; ozone in methanol; dichloromethane T=-78°C;
参考文献
Clive, Derrick L. J.; Yeh, Vince S. C.
Tetrahedron Letters, 1998 , vol. 39, # 27 p. 4789 - 4792
反应条件
1: With ozone in dichloromethane T=-78°C; Ozonolysis; 0.166667 h; 2: With dimethylsulfide in dichloromethane T=20°C; Reduction; 2 h;
参考文献
Karstens, Willem F. J.; Moolenaar, Marinus J.; Rutjes, Floris P. J. T.; Grabowska, Urszula; Speckamp, W. Nico; Hiemstra, Henk
Tetrahedron Letters, 1999 , vol. 40, # 49 p. 8629 - 8632
反应条件
hydrogen; palladium on activated charcoal in methanol 1 h;
参考文献
Moreno-Vargas, Antonio J.; Vogel, Pierre
Tetrahedron Asymmetry, 2003 , vol. 14, # 20 p. 3173 - 3176
反应条件
triethylamine in dichloromethane T=35°C; Acylation; 12 h;
参考文献
Tetrahedron Asymmetry, , vol. 11, # 12 p. 2525 - 2529
反应条件
1: Et3N / CH2Cl2 / 20 h / 20 °C 2: 90 percent / hydrogen / Pd/C / ethanol; ethyl acetate / 10 h / 2844.31 Torr View Scheme
参考文献
Tetrahedron Letters, , vol. 42, # 23 p. 3947 - 3949
