(R)-1-苯基-1,2-乙二醇合成路线 (共 159 条)
反应条件
water T=37°C; rabbit liver microsomal epoxide hydrolase; Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 31, # 12 p. 828 - 831
反应条件
copper(II) sulfate in methanol T=4°C; 3 h;
参考文献
Brown, Sean P.; Brochu, Michael P.; Sinz, Christopher J.; MacMillan, David W. C.
Journal of the American Chemical Society, 2003 , vol. 125, # 36 p. 10808 - 10809
反应条件
1: With hydrogen; bis(norbornadiene)rhodium(I) tetrafluoroborate; (S,R)-Walphos (SL-W001-1) P=11400.8 Torr; 2: With dihydrogen peroxide Product distribution / selectivity;
参考文献
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
Patent: WO2005/12209 A2, 2005 ;
Location in patent: Page/Page column 61 ;
反应条件
sodium chloride in water
参考文献
Bayer Aktiengesellschaft
Patent: US6472570 B1, 2002 ;
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=-78 - 20°C; Inert atmosphere;
参考文献
Ishihara, Kazuaki; Kosugi, Yuji; Umemura, Shuhei; Sakakura, Akira
Organic Letters, 2008 , vol. 10, # 15 p. 3191 - 3194
反应条件
sodium tetrahydroborate in methanol T=20°C;
参考文献
Tetrahedron Asymmetry, , vol. 15, # 19 p. 3059 - 3072
参考文献
Council of Scientific and Industrial Research
Patent: US6552234 B1, 2003 ;
反应条件
zirconium tetrachloride in methanol T=35°C; 3 h;
参考文献
Singh, Surendra; Duffy, Colm D.; Shah, Syed Tasadaque A.; Guiry, Patrick J.
Journal of Organic Chemistry, 2008 , vol. 73, # 16 p. 6429 - 6432
反应条件
zirconium tetrachloride in methanol T=35°C; 4 h;
参考文献
Singh, Surendra; Duffy, Colm D.; Shah, Syed Tasadaque A.; Guiry, Patrick J.
Journal of Organic Chemistry, 2008 , vol. 73, # 16 p. 6429 - 6432
反应条件
molybdenum hexacarbonate in water; acetonitrile T=85°C; 1.5 h; Inert atmosphere;
参考文献
Tetrahedron, , vol. 68, # 17 p. 3468 - 3479