(R)-1-苯基-1,2-乙二醇合成路线 (共 159 条)
反应条件
potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate in tetrahydrofuran; methanol T=50°C; 10 h; Title compound not separated from byproducts.;
参考文献
Journal of the American Chemical Society, , vol. 124, # 8 p. 1584 - 1585
反应条件
styrene monooxygenase in α-n-hexadecene 24 h; aq. buffer; optical yield given as percent ee;
参考文献
Xu, Yi; Jia, Xin; Panke, Sven; Li, Zhi
Chemical Communications, 2009 , # 12 p. 1481 - 1483
反应条件
DAHP; [14C]-Sucrose in ethanol; water T=28 - 30°C; 18 h; Microbiological reaction; optical yield given as percent ee;
参考文献
Bosiak, Mariusz J.; Pakulski, Marcin M.
Synthesis, 2011 , # 2 art. no. P14610SS, p. 316 - 324
反应条件
cell free extract from Candida parapsilosis CICC 1627 in aq. phosphate buffer T=30°C; pH=6.5; 48 h; Microbiological reaction; Reagent/catalyst; enantioselective reaction;
参考文献
Nie, Yao; Xu, Yan; Mu, Xiao Qing
Organic Process Research and Development, 2004 , vol. 8, # 2 p. 246 - 251
反应条件
Tris-HCl buffer; Sphingomonas sp. HXN-200 cell free extract in hexane T=25°C; pH=7.5; 4 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 17, # 1 p. 47 - 52
反应条件
whole cells of P. putida UV4 (mutant strain, containing TDO); sodium 2-oxopropanoate; oxygen in phosphate buffer; ethanol T=30°C; pH=7.2; 24 h;
参考文献
Boyd, Derek R.; Sharma, Narain D.; Bowers, Nigel I.; Brannigan, Ian N.; Groocock, Melanie R.; Malone, John F.; McConville, Gareth; Allen, Christopher C. R.
Advanced Synthesis and Catalysis, 2005 , vol. 347, # 7-8 p. 1081 - 1089
反应条件
sodium carbonate; (S)-4,4-Br2-4,5-dihydro-3H-dinaphtho[2,1-c:1',2'-e]stannepin in tetrahydrofuran; water T=-10°C; 14 h; Title compound not separated from byproducts.;
参考文献
Organic Letters, , vol. 1, # 7 p. 969 - 972
反应条件
epoxide hydrolase from Agrobacterium radiobacter AD1; halohydrin dehalogenase from Agrobacterium radiobacter AD1; Tris-SO4 buffer in water T=30°C; kinetic resolution; pH=7.5;
参考文献
Lutje Spelberg, Jeffrey H.; Van Hylckama Vlieg, Johan E. T.; Bosma, Tjibbe; Kellogg, Richard M.; Janssen, Dick B.
Tetrahedron Asymmetry, 1999 , vol. 10, # 15 p. 2863 - 2870
反应条件
Agrobacterium radiobacter AD1 epoxide hydrolase; TE buffer in acetonitrile T=30°C; Enzyme kinetics; Further Variations:Reagents;
参考文献
Journal of the American Chemical Society, , vol. 121, # 32 p. 7417 - 7418
反应条件
potassium hydroxide in methanol
参考文献
Journal of the American Chemical Society, , vol. 123, # 40 p. 9738 - 9742