(R)-1-苯基-1,2-乙二醇合成路线 （共 159 条）
反应条件
1: L-proline / CHCl3 / 2 h / 4 °C 2: 137.4 mg / NaBH4 / ethanol / 0.33 h / 0 °C 3: 52 percent / CuSO4 / methanol / 3 h / 4 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 125, # 36 p. 10808 - 10809
反应条件
1: 137.4 mg / NaBH4 / ethanol / 0.33 h / 0 °C 2: 52 percent / CuSO4 / methanol / 3 h / 4 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 125, # 36 p. 10808 - 10809
反应条件
1.1: O3 / CH2Cl2; methanol 1.2: NaBH4 / propan-2-ol 2.1: KOH / methanol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 123, # 40 p. 9738 - 9742
反应条件
1.1: 76 percent / DMAP; pyridine / CH2Cl2 / 16 h / Heating 2.1: ozone / CH2Cl2; methanol / -78 °C 2.2: 73 percent / Me2S / CH2Cl2; methanol / 3 h / 20 °C 3.1: KHMDS; 18-crown-6 / tetrahydrofuran / 0.5 h / -78 °C 3.2: tetrahydrofuran / 3 h / -78 °C 4.1: O3 / CH2Cl2; methanol 4.2: NaBH4 / propan-2-ol 5.1: KOH / methanol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 123, # 40 p. 9738 - 9742
反应条件
1.1: KHMDS; 18-crown-6 / tetrahydrofuran / 0.5 h / -78 °C 1.2: tetrahydrofuran / 3 h / -78 °C 2.1: O3 / CH2Cl2; methanol 2.2: NaBH4 / propan-2-ol 3.1: KOH / methanol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 123, # 40 p. 9738 - 9742
反应条件
1.1: ozone / CH2Cl2; methanol / -78 °C 1.2: 73 percent / Me2S / CH2Cl2; methanol / 3 h / 20 °C 2.1: KHMDS; 18-crown-6 / tetrahydrofuran / 0.5 h / -78 °C 2.2: tetrahydrofuran / 3 h / -78 °C 3.1: O3 / CH2Cl2; methanol 3.2: NaBH4 / propan-2-ol 4.1: KOH / methanol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 123, # 40 p. 9738 - 9742
反应条件
sodium hydroxide; dihydrogen peroxide T=20°C; 3 h; Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 126, # 47 p. 15338 - 15339
反应条件
1: 100 percent / NaBH4 / methanol / 20 °C 2: 43 percent / [bmim]PF6 / lipase PS-C / 10 h / 20 °C 3: 94 percent / K2CO3 / methanol / 4 h View Scheme
参考文献
Tetrahedron Letters, , vol. 45, # 48 p. 8801 - 8805
反应条件
SgcF epoxide hydrolase from the C-1027 biosynthetic gene cluster; H218O T=25°C; pH=8; 8 h; aq. phosphate buffer;
参考文献
Journal of the American Chemical Society, , vol. 131, # 45 p. 16410 - 16417
反应条件
dimethylsulfide borane complex; (S)-Ph(NH)S(O)CH2C(Ph)2OH in toluene 3 h; Ambient temperature; Yield given. Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 34, # 38 p. 6041 - 6044
