(R)-1-苯基-1,2-乙二醇合成路线 （共 159 条）
反应条件
1: 97 percent / [bmim]Br / 0.5 h / 20 °C 2: 100 percent / NaBH4 / methanol / 20 °C 3: 43 percent / [bmim]PF6 / lipase PS-C / 10 h / 20 °C 4: 94 percent / K2CO3 / methanol / 4 h View Scheme
参考文献
Tetrahedron Letters, , vol. 45, # 48 p. 8801 - 8805
反应条件
water; acetic acid; zinc in tetrahydrofuran T=50 - 60°C; 23 h; Overall yield = 47 percent; Overall yield = 7.2 mg;
参考文献
European Journal of Organic Chemistry, , # 25 p. 5585 - 5589
反应条件
Geotrichum sp. 38 in dimethyl sulfoxide T=30°C; 16 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron, , vol. 54, # 43 p. 13059 - 13072
反应条件
Coprinus peroxidase; 2-methoxy-phenol in water T=20°C; 20 h; pH 7.0; Further byproducts given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 64, # 13 p. 4834 - 4839
反应条件
in tetrahydrofuran; hydrogenchloride Hydrolysis;
参考文献
European Journal of Organic Chemistry, , # 11 p. 2885 - 2892
反应条件
sodium hydroxide in diethyl ether T=20°C; 2 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 12, # 12 p. 1801 - 1806
反应条件
1: 60 percent / toluene; diethyl ether / 0.42 h / -20 °C 2: Mo(CO)6 / acetonitrile; H2O / 1 h / 85 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 69, # 17 p. 5595 - 5607
反应条件
1: With sodium tetrahydroborate in tetrahydrofuran T=0°C; 2: With hydrogenchloride; water in tetrahydrofuran; ethyl acetate 0.166667 h; optical yield given as percent ee;
参考文献
Tetrahedron, , vol. 65, # 25 p. 4801 - 4807
反应条件
SgcF epoxide hydrolase from the C-1027 biosynthetic gene cluster; H218O T=25°C; pH=8; 8 h; aq. phosphate buffer; optical yield given as percent eeregiospecific reaction;
参考文献
Journal of the American Chemical Society, , vol. 131, # 45 p. 16410 - 16417
反应条件
T=37°C; 0.5 h; other substituted ethene oxides; rabbit liver microsomal epoxide hydrolase (mEH; KM, Vmax;
参考文献
Bellucci; Chiappe; Cordoni; Marioni
Tetrahedron Asymmetry, 1993 , vol. 4, # 6 p. 1153 - 1160
