(R)-1-苯基-1,2-乙二醇合成路线 (共 159 条)
反应条件
1: aq. HgCl2 / acetonitrile / 6 h / 20 °C 2: LiAlH4 / tetrahydrofuran / 3 h / 0 - 20 °C View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 2, # 15 p. 2168 - 2169
反应条件
1: With ozone in methanol; dichloromethane T=-78°C; 2: With sodium tetrahydroborate
参考文献
Angewandte Chemie - International Edition, , vol. 50, # 34 p. 7906 - 7909
反应条件
1: With glycerol dehydrogenase from cellulomonas spp.; ABTS; Reduced nicotinamide-adenine dinucleotide in aq. buffer T=25°C; Resolution of racemateElectrochemical reactionEnzymatic reaction; 2: With nicotinamide adenine dinucleotide in aq. buffer T=25°C; Electrochemical reactionResolution of racemate;
参考文献
Organic Process Research and Development, , vol. 8, # 2 p. 213 - 218
反应条件
(2S,3R)-(-)-2-amino-3-methyl-1,1-diphenylpentanol*borane in tetrahydrofuran T=30°C; 1 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2039 - 2044
反应条件
sodium hydroxide in methanol T=25°C; 3 h; Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 18 p. 2395 - 2398
反应条件
sodium hydroxide in methanol T=25°C; 3 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 18 p. 2395 - 2398
参考文献
Tetrahedron: Asymmetry, , vol. 4, # 6 p. 1365 - 1386
反应条件
sodium hydroxide in methanol T=50°C; 2 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Agricultural and Biological Chemistry, , vol. 46, # 5 p. 1153 - 1157
反应条件
sodium phosphate buffer; enzymatic extract of S. racemosum in dimethyl sulfoxide T=27°C; regioselectivity of the biohydrolysis; Product distributionMechanism;
参考文献
Journal of Organic Chemistry, , vol. 63, # 11 p. 3532 - 3537
反应条件
Geotrichum sp; water in N,N-dimethyl-formamide T=30°C; Reduction; hydrolysis; 18 h; Title compound not separated from byproducts;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 8, # 5 p. 1129 - 1137