反应条件
1.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 50 °C
1.2: 5 h / 75 °C
2.1: water; sodium hydroxide / tert-butyl methyl ether / 20 °C
3.1: benzenesulfonyl chloride; triethylamine / tert-butyl methyl ether; toluene / 2 h / 80 °C
3.2: 50 °C
View Scheme
参考文献
SANOFI; BON, Xavier; LEROY, Corinne
Patent: US2013/23677 A1, 2013 ;