hydrogenchloride; ethanethioamide in N,N-dimethyl-formamide T=45°C; 40 h;

1: palladium diacetate / dimethyl sulfoxide / 4 h / 40 - 45 °C 2: potassium carbonate; potassium iodide / dimethyl sulfoxide / 16 h / 70 - 75 °C 3: hydrogenchloride; ethanethioamide / isopropyl alcohol / 14 h / 40 - 45 °C View Scheme

1: N-bromosuccinmide; trifluorormethanesulfonic acid / acetonitrile / -15 - 30 °C 2: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 12 h / 70 - 75 °C 3: sodium carbonate / palladium diacetate / N,N-dimethyl-formamide / 18 h / 140 - 145 °C 4: hydrogenchloride; ethanethioamide / isopropyl alcohol / 14 h / 40 - 45 °C View Scheme

1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 12 h / 70 - 75 °C 2: sodium carbonate / palladium diacetate / N,N-dimethyl-formamide / 18 h / 140 - 145 °C 3: hydrogenchloride; ethanethioamide / isopropyl alcohol / 14 h / 40 - 45 °C View Scheme

1: sodium carbonate / palladium diacetate / N,N-dimethyl-formamide / 18 h / 140 - 145 °C 2: hydrogenchloride; ethanethioamide / isopropyl alcohol / 14 h / 40 - 45 °C View Scheme

1: 2.) K2CO3 / 1.) DMSO, 100 deg C, 1 h, 2.) 6 h; 70 deg C 2: 85 percent / thioacetamide, HCl / dimethylformamide / 40 h / 45 °C View Scheme

1: potassium carbonate; potassium iodide / dimethyl sulfoxide / 16 h / 70 - 75 °C 2: hydrogenchloride; ethanethioamide / isopropyl alcohol / 14 h / 40 - 45 °C View Scheme

in ethanol T=100°C; 2 h;