pyridine T=200°C; 20 h;

cesium fluoride in acetonitrile 3 h; Reflux;

1: 78 percent / aq. hydrochloric acid; methyl nitrite / methanol / 0.25 h 2: 80 percent / formaldehyde; aq. hydrochloric acid 3: 72 percent / glacial acetic acid; hydrogen peroxide / cooling 4: 70 percent / 4 h / 200 °C 5: anhydrous aluminium chloride / chlorobenzene / 4 h / Heating 6: sodium hydroxide; Adogen 464 / H2O / 1 h View Scheme

sodium hydroxide; adogen 464 in water 1 h;