3-吡啶-4-基-1,2,4-噁二唑-5-羧酸乙酯合成路线 （共 2 条）
反应条件
pyridine in chloroform T=20°C; 5.5 h; Reflux;
参考文献
Koryakova, Angela G.; Ivanenkov, Yan A.; Ryzhova, Elena A.; Bulanova, Elena A.; Karapetian, Ruben N.; Mikitas, Olga V.; Katrukha, Eugeny A.; Kazey, Vasily I.; Okun, Ilya; Kravchenko, Dmitry V.; Lavrovsky, Yan V.; Korzinov, Oleg M.; Ivachtchenko, Alexandre V.
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 12 p. 3661 - 3666
反应条件
1.1: hydroxylamine hydrochloride; potassium carbonate / ethanol / 16 h / Heating 2.1: 4A molecular sieves; NaH / tetrahydrofuran / 0.1 h 2.2: 28 percent / tetrahydrofuran / 1 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 47, # 14 p. 3642 - 3657
