sodium tris(acetoxy)borohydride in ethyl acetate T=20°C;

1: N-(4-acetylphenyl)piperazine With Nafion-SO2-NH-(m-C6H4)-SO2-CH=CH2 in N,N-dimethyl-formamide Addition; 72 h; 2: benzyl bromide in N,N-dimethyl-formamide Alkylation; quaternarysation; 24 h; 3: With N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide Elimination; 24 h;

N-ethyl-N,N-diisopropylamine 48 h; Heating / reflux;