4-氨基-2,3-二氟苯酚合成路线 (共 4 条)
反应条件
hydrogen; palladium 10 on activated carbon in methanol P=1551.49 Torr; 2 h;
参考文献
DECIPHERA PHARMACEUTICALS, LLC; FLYNN, Daniel L.; PETILLO, Peter A.; KAUFMAN, Michael D.
Patent: WO2013/36232 A2, 2013 ;
Location in patent: Paragraph 00279 ;
反应条件
hydrogen; palladium 10 on activated carbon in methanol; ethyl acetate 12 h;
参考文献
US2005/245530 A1, ;
Page/Page column 93 ;
US 20050245530 A1
反应条件
hydrogen; palladium 10 on activated carbon in ethanol T=20°C; P=750.075 Torr; 18 h;
参考文献
Bayer Chemicals AG
Patent: EP1514865 A1, 2005 ;
Location in patent: Page/Page column 9 ;
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 8 h / 20 °C 2: hydrogen; palladium 10 on activated carbon / methanol / 2 h View Scheme