2’-O-(2-甲氧基乙基)-5-甲基尿苷合成路线 （共 48 条）
反应条件
1: 1,8-diazabicyclo<5.4.0>undec-7-ene / acetonitrile / 10 h 2: 98 percent / 30percent NaOMe / methanol / 3 h / Ambient temperature 3: 83 percent / NaH / tetrahydrofuran / 40 - 70 °C 4: H2 / 5percent Pd/C / tetrahydrofuran / Ambient temperature 5: 30percent NaOMe / methanol / Ambient temperature; pH 11 6: 94 percent / H2, NaOAc / 5percent Pd/C / methanol / 45 °C / 2250.2 Torr View Scheme
参考文献
Helvetica Chimica Acta, , vol. 78, # 2 p. 486 - 504
反应条件
1: 83 percent / NaH / tetrahydrofuran / 40 - 70 °C 2: H2 / 5percent Pd/C / tetrahydrofuran / Ambient temperature 3: 30percent NaOMe / methanol / Ambient temperature; pH 11 4: 94 percent / H2, NaOAc / 5percent Pd/C / methanol / 45 °C / 2250.2 Torr View Scheme
参考文献
Helvetica Chimica Acta, , vol. 78, # 2 p. 486 - 504
反应条件
1: 98 percent / 30percent NaOMe / methanol / 3 h / Ambient temperature 2: 83 percent / NaH / tetrahydrofuran / 40 - 70 °C 3: H2 / 5percent Pd/C / tetrahydrofuran / Ambient temperature 4: 30percent NaOMe / methanol / Ambient temperature; pH 11 5: 94 percent / H2, NaOAc / 5percent Pd/C / methanol / 45 °C / 2250.2 Torr View Scheme
参考文献
Helvetica Chimica Acta, , vol. 78, # 2 p. 486 - 504
反应条件
1: H2 / 5percent Pd/C / tetrahydrofuran / Ambient temperature 2: 30percent NaOMe / methanol / Ambient temperature; pH 11 3: 94 percent / H2, NaOAc / 5percent Pd/C / methanol / 45 °C / 2250.2 Torr View Scheme
参考文献
Helvetica Chimica Acta, , vol. 78, # 2 p. 486 - 504
反应条件
1.1: 70 percent / c-C5H5N / CH2Cl2 / 5 h / 20 °C 2.1: 100 percent / Amberlit IR-120 / methanol; tetrahydrofuran; H2O / 6.5 h / 60 °C 3.1: NaIO4 / ethanol; H2O / 24 h / 20 °C 3.2: HCl / acetone / 24 h / 20 °C 3.3: 82 percent / c-C5H5N / 4 h / 40 °C 4.1: 88 percent / tin(II) chloride / acetonitrile / 5 h / 65 °C 5.1: 91 percent / sodium methoxide / methanol / 1 h / 20 °C View Scheme
参考文献
Helvetica Chimica Acta, , vol. 86, # 1 p. 204 - 209
反应条件
1.1: 87 percent / AcOH / H2O / 2 h / 40 °C 2.1: 70 percent / c-C5H5N / CH2Cl2 / 5 h / 20 °C 3.1: 100 percent / Amberlit IR-120 / methanol; tetrahydrofuran; H2O / 6.5 h / 60 °C 4.1: NaIO4 / ethanol; H2O / 24 h / 20 °C 4.2: HCl / acetone / 24 h / 20 °C 4.3: 82 percent / c-C5H5N / 4 h / 40 °C 5.1: 88 percent / tin(II) chloride / acetonitrile / 5 h / 65 °C 6.1: 91 percent / sodium methoxide / methanol / 1 h / 20 °C View Scheme
参考文献
Helvetica Chimica Acta, , vol. 86, # 1 p. 204 - 209
反应条件
1.1: 100 percent / Amberlit IR-120 / methanol; tetrahydrofuran; H2O / 6.5 h / 60 °C 2.1: NaIO4 / ethanol; H2O / 24 h / 20 °C 2.2: HCl / acetone / 24 h / 20 °C 2.3: 82 percent / c-C5H5N / 4 h / 40 °C 3.1: 88 percent / tin(II) chloride / acetonitrile / 5 h / 65 °C 4.1: 91 percent / sodium methoxide / methanol / 1 h / 20 °C View Scheme
参考文献
Helvetica Chimica Acta, , vol. 86, # 1 p. 204 - 209
反应条件
1: 88 percent / tin(II) chloride / acetonitrile / 5 h / 65 °C 2: 91 percent / sodium methoxide / methanol / 1 h / 20 °C View Scheme
参考文献
Helvetica Chimica Acta, , vol. 86, # 1 p. 204 - 209
反应条件
1: With dichloro-acetic acid; pyrrole in dichloromethane 2: With triethylamine in methanol; dichloromethane
参考文献
Tetrahedron Letters, , vol. 53, # 35 p. 4669 - 4672
反应条件
1: With dichloro-acetic acid; pyrrole in dichloromethane 2: With triethylamine in methanol; dichloromethane
参考文献
Tetrahedron Letters, , vol. 53, # 35 p. 4669 - 4672
