5-甲氧基-3-甲基-1H-吲哚-2-羧酸合成路线 （共 6 条）
反应条件
potassium hydroxide in ethanol 1 h; Heating;
参考文献
Zhao, Shuo; Liao, Xuebin; Wang, Tao; Flippen-Anderson, Judith; Cook, James M.
Journal of Organic Chemistry, 2003 , vol. 68, # 16 p. 6279 - 6295
反应条件
1.1: aq. HCl; NaNO2 / H2O / 0.25 h / 0 °C 1.2: KOH / ethanol; H2O / 15 h / 0 - 4 °C / pH 5 - 6 1.3: 74 percent / HCl / ethanol / 2 h / 78 °C 2.1: 100 percent / KOH / ethanol / 1 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 68, # 16 p. 6279 - 6295
反应条件
1: trichlorophosphate / N,N-dimethyl-formamide / 2.5 h / 110 °C / |Cooling with ice 2: triethylsilane; trifluoroacetic acid / 5 h / 20 °C 3: lithium hydroxide hydrate / tetrahydrofuran; water / 3 h / 20 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 68, p. 372 - 384
反应条件
1: triethylsilane; trifluoroacetic acid / 5 h / 20 °C 2: lithium hydroxide hydrate / tetrahydrofuran; water / 3 h / 20 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 68, p. 372 - 384
反应条件
phosphorus pentachloride; acetyl chloride und Behandeln des Reaktionsprodukts mit Lithiumalanat und tert-Butylalkohol in 1,2-Dimethoxy-aethan;
参考文献
Sato; Matsumoto
Takamine Kenkyusho Nenpo, 1959 , vol. 11, p. 33,35
Chem.Abstr., 1961 , p. 5456
反应条件
quinoline; copper 2.5 h; Heating;
参考文献
Zhao, Shuo; Liao, Xuebin; Wang, Tao; Flippen-Anderson, Judith; Cook, James M.
Journal of Organic Chemistry, 2003 , vol. 68, # 16 p. 6279 - 6295
