2,2-二甲基-4-戊烯酸合成路线 （共 36 条）
反应条件
sodium hydroxide in methanol; water T=80°C;
参考文献
Crimmins, Michael T.; Carroll, Charlotte A.; Wells, Angela J.
Tetrahedron Letters, 1998 , vol. 39, # 39 p. 7005 - 7008
反应条件
n-butyllithium; sodium hydride; diisopropylamine in tetrahydrofuran; hexane 1.) 0 deg C, 25 min, then room temp., 2.5 h; 2.) 0 deg C, 1 h, then 25 deg C, 12 h;
参考文献
Crimmins, Michael T.; Carroll, Charlotte A.; Wells, Angela J.
Tetrahedron Letters, 1998 , vol. 39, # 39 p. 7005 - 7008
反应条件
sodium hydroxide in methanol; water T=80°C;
参考文献
Baader, Sabrina; Ohlmann, Dominik M.; Goossen, Lukas J.
Chemistry - A European Journal, 2013 , vol. 19, # 30 p. 9807 - 9810
反应条件
sodium tetrahydroborate in tetrahydrofuran 0.166667 h; Ambient temperature;
参考文献
Comasseto, Joao V.; Petragnani, Nicola
Synthetic Communications, 1983 , vol. 13, # 11 p. 889 - 900
反应条件
potassium hydroxide; ethylene glycol
参考文献
Journal of the American Chemical Society, , vol. 77, p. 1092
参考文献
Journal of the American Chemical Society, , vol. 81, p. 3379,3381
反应条件
1: With n-butyllithium; cyclohexyl(iPr)NLi in tetrahydrofuran Ireland-type Claisen rearrangement; 2: With chloro-trimethyl-silane in methanol Further stages.;
参考文献
Andersen, Rosaleen J.; Ashwell, Susan; Garnett, Ian; Golding, Bernard T.
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 24 p. 4488 - 4498
反应条件
in tetrahydrofuran 1.) -30 deg C, 1 h, 2.) 0 deg C, 1 h;
参考文献
Fujisawa, Tamotsu; Sato, Toshio; Kawara, Tatsuo; Kawashima, Masatoshi
Tetrahedron Letters, 1980 , vol. 21, p. 2181 - 2184
反应条件
water in 1,4-dioxane T=25°C; acid-catalyzed hydrolysis; Rate constant;
参考文献
Journal of Organic Chemistry, , vol. 47, # 8 p. 1567 - 1571
反应条件
tetrakis(triphenylphosphine) palladium(0) in dichloromethane 22 h; Heating;
参考文献
Journal of Organometallic Chemistry, , vol. 624, # 1-2 p. 186 - 202
