2,3,3-三甲基-3H-吲哚合成路线 （共 91 条）
反应条件
Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Doepp, Dietrich; Rehmer, Gerd; Brueggemann, Helmut
Chemische Berichte, 1988 , vol. 121, p. 1651 - 1656
反应条件
1: 84 percent / NaNO3, H2SO4 / below 0 deg C 2: 61 percent / acetone / 12 h / Heating 3: 85 percent / piperidine / ethanol / 1.5 h / Heating View Scheme
参考文献
Pottier, E.; Sergent, M.; Luu, R. Phan Tan; Guglielmetti, R.
Bulletin des Societes Chimiques Belges, 1992 , vol. 101, # 8 p. 719 - 740
反应条件
0.583333 h; Microwave irradiation;
参考文献
Kienzler, Andrea Altevogt Nee; Flehr, Roman; Gehne, Soeren; Kumke, Michael U.; Bannwarth, Willi
Helvetica Chimica Acta, 2012 , vol. 95, # 4 p. 543 - 555
反应条件
1: 1 h / 60 °C / Inert atmosphere 2: sodium hydroxide / diethyl ether; water / 0.5 h 3: ethanol / 24 h / Reflux View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 6 p. 1162 - 1171
反应条件
in acetonitrile 15 h; Reflux;
参考文献
Samanta, Animesh; Maiti, Kaustabh Kumar; Soh, Kiat-Seng; Liao, Xiaojun; Vendrell, Marc; Dinish; Yun, Seong-Wook; Bhuvaneswari, Ramaswamy; Kim, Hyori; Rautela, Shashi; Chung, Junho; Olivo, Malini; Chang, Young-Tae
Angewandte Chemie - International Edition, 2011 , vol. 50, # 27 p. 6089 - 6092
反应条件
1: 2,3,3-trimethyl-(3H)-indoleine; 2-bromo-1-ethanol in acetonitrile 24 h; RefluxInert atmosphere; 2: With potassium hydroxide in water T=20°C; 0.5 h; 3: 2-hydroxy-5-nitro-benzaldehyde in ethanol 3 h; RefluxInert atmosphere;
参考文献
Zhu, Ming-Qiang; Zhang, Guo-Feng; Hu, Zhe; Aldred, Matthew P.; Li, Chong; Gong, Wen-Liang; Chen, Tao; Huang, Zhen-Li; Liu, Shiyong
Macromolecules, 2014 , vol. 47, # 5 p. 1543 - 1552
反应条件
1: 61 percent / xylene / 0.25 h / Ambient temperature; Irradiation 2: 88 percent / piperidine / ethanol / 0.17 h / Ambient temperature; Irradiation View Scheme
参考文献
Sakuragi; Aoki; Tamaki; Ichimura
Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 1 p. 74 - 79
反应条件
in acetonitrile 24 h; Reflux;
参考文献
Tyler, Andrew R.; Okoh, Adeyi Okoh; Lawrence, Clare L.; Jones, Vicky C.; Moffatt, Colin; Smith, Robert B.
European Journal of Medicinal Chemistry, 2013 , vol. 64, p. 222 - 227
反应条件
1: 69 percent / acetonitrile / 24 h / Heating
2: 88 percent / potassium hydroxide / H2O / 0.17 h / 20 °C
View Scheme
参考文献
Shiraishi, Yasuhiro; Itoh, Masataka; Hirai, Takayuki
Physical Chemistry Chemical Physics, 2010 , vol. 12, # 41 p. 13737 - 13745
反应条件
1: in acetonitrile
24 h; Heating;
2: With potassium hydroxide in water
T=20°C; 0.5 h;
参考文献
Sakata, Tomoyo; Yan, Yuling; Marriott, Gerard
Journal of Organic Chemistry, 2005 , vol. 70, # 6 p. 2009 - 2013
