2,3,3-三甲基-3H-吲哚合成路线 （共 91 条）
反应条件
ammonium hydroxide
1.) reflux; Yield given. Multistep reaction;
参考文献
Bartnik, Romuald; Mloston, Grzegorz; Lesniak, Stanislaw
Polish Journal of Chemistry, 1991 , vol. 65, # 11 p. 1957 - 1961
反应条件
1: 5.5 h / 135 - 140 °C
2: aq. KOH / acetone / 40 °C
View Scheme
参考文献
Shachkus, A. A.; Degutis, Yu. A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1986 , vol. 22, # 11 p. 1198 - 1202
Khimiya Geterotsiklicheskikh Soedinenii, 1986 , vol. 22, # 11 p. 1485 - 1489
反应条件
potassium hydroxide
1) 135 - 145 deg C, 5.5 h; 2) 40 deg C;;
参考文献
Shachkus, A. A.; Degutis, Yu. A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1986 , vol. 22, # 11 p. 1198 - 1202
Khimiya Geterotsiklicheskikh Soedinenii, 1986 , vol. 22, # 11 p. 1485 - 1489
反应条件
in ethanol
5 h; Reflux;
参考文献
Andersson, Johanna; Li, Shiming; Lincoln, Per; Andreasson, Joakim
Journal of the American Chemical Society, 2008 , vol. 130, # 36 p. 11836 - 11837
反应条件
1: 92 percent / CHCl3 / 48 h / 65 - 75 °C
2: 50 percent / NaOH; water / 2 h / 20 °C
3: 57 percent / ethanol / 12 h / 70 - 75 °C
View Scheme
参考文献
Samoilova, N.P.; Bobyleva, G.K.; Gal'bershtam, M.P.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1980 , vol. 16, # 1 p. 41 - 44
Khimiya Geterotsiklicheskikh Soedinenii, 1980 , vol. 16, # 1 p. 51 - 54
反应条件
2: KOH-solution
View Scheme
参考文献
Murata, Tsuyoshi; Nishimura, Kazukuni; Enomoto, Yuichiro; Honda, Genki; Shimizu, Yasuhito; Otsuka, Akihiro; Saito, Gunzi
Bulletin of the Chemical Society of Japan, 2008 , vol. 81, # 7 p. 869 - 884
反应条件
in chloroform
T=65 - 75°C; 48 h;
参考文献
Kang, Heekyoung; Lee, Youn-Sik; Kim, Eunkyoung; Kang, Yongku; Kim, Dong Wook; Lee, Changjin
Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, 2003 , vol. 406, # PART 2 p. 169/[363]-179/[373]
反应条件
1: 92 percent / CHCl3 / 48 h / 65 - 75 °C
2: 50 percent / NaOH; water / 2 h / 20 °C
View Scheme
参考文献
Hirano, Masafumi; Miyashita, Akira; Nohira, Hiroyuki
Chemistry Letters, 1991 , # 2 p. 209 - 212
反应条件
1: sodium nitrate; sulfuric acid / 1 h / 0 - 5 °C
2: hydrogenchloride; SnCl2·2H2O / water / 2 h / Reflux
View Scheme
参考文献
LABORATOIRES SYNTH-INNOVE
Patent: US2012/45851 A1, 2012 ;
反应条件
potassium iodide in acetonitrile
T=23 - 85°C; 72 h; Inert atmosphere;
参考文献
Simmons, Rebecca L.; Yu, Robert T.; Myers, Andrew G.
Journal of the American Chemical Society, 2011 , vol. 133, # 40 p. 15870 - 15873
