6-氯喹唑啉-2,4-二酮合成路线

参考文献

KALYPSYS, INC.; BORCHARDT, Allen; DAVIS, Robert; BEAUREGARD, Clay; BECKER, Daniel; GAMACHE, Daniel; NOBLE, Stewart, A.; HELLBERG, Mark, R.; KLIMKO, Peter, G.; ZHIHAI, Qui; PAYNE, Joseph, E.; YANNI, John
Patent: WO2011/112731 A2, 2011 ;
Location in patent: Page/Page column 79 ;
WO 2011/112731 A2

5202-85-72-氨基-5-氯苯甲酰胺

1640-60-46-氯喹唑啉-2,4-二酮

参考文献

American Home Products Corporation
Patent: US5187168 A1, 1993 ;

917-61-3氰酸钠+

635-21-22-氨基-5-氯苯甲酸

1640-60-46-氯喹唑啉-2,4-二酮

参考文献

ARDELYX, INC.; CHARMOT, Dominique; JACOBS, Jeffrey, W.; LEADBETTER, Michael, Robert; NAVRE, Marc; CARRERAS, Chris; BELL, Noah
Patent: WO2010/78449 A2, 2010 ;
Location in patent: Page/Page column 235 ;
WO 2010/078449 A2

124-38-9二氧化碳+

5922-60-12-氨基-5-氯苯腈

1640-60-46-氯喹唑啉-2,4-二酮

参考文献

Mizuno, Takumi; Nakai, Takeo; Mihara, Masatoshi
Heteroatom Chemistry, 2012 , vol. 23, # 3 p. 276 - 280

590-28-3氰酸钾+

635-21-22-氨基-5-氯苯甲酸

1640-60-46-氯喹唑啉-2,4-二酮

参考文献

Nikpour, Farzad; Paibast, Touraj
Chemistry Letters, 2005 , vol. 34, # 10 p. 1438 - 1439

635-21-22-氨基-5-氯苯甲酸

1640-60-46-氯喹唑啉-2,4-二酮

参考文献

Tetrahedron, , vol. 53, # 25 p. 8457 - 8478

75-44-5光气+

5202-85-72-氨基-5-氯苯甲酰胺

1640-60-46-氯喹唑啉-2,4-二酮

参考文献

US2002/25968 A1, ;

3603-10-9

1640-60-46-氯喹唑啉-2,4-二酮

参考文献

Nikpour, Farzad; Havasi, Forugh; Arzegar, Zeinab
Heterocycles, 2012 , vol. 85, # 11 p. 2745 - 2748,4
Title/Abstract Full Text Show Details
Nikpour, Farzad; Havasi, Forugh; Arzegar, Zeinab
Heterocycles, 2012 , vol. 85, # 11 p. 2745 - 2748

5922-60-12-氨基-5-氯苯腈+

68-12-2N,N-二甲基甲酰胺

16064-14-56-氯-4(3H)-喹唑啉酮+

1640-60-46-氯喹唑啉-2,4-二酮

参考文献

Organic Letters, , vol. 11, # 6 p. 1193 - 1196

192570-30-2

1640-60-46-氯喹唑啉-2,4-二酮

参考文献

Michel, Justine; Gueguen, Genevieve; Vercauteren, Joseph; Moreau, Serge
Tetrahedron, 1997 , vol. 53, # 25 p. 8457 - 8478