(R)-(+)-1-异氰酸苯丙酯合成路线 （共 5 条）
反应条件
hydrogenchloride 1.) Et2O, 30 min, 2.) toluene, a) reflux, 3 h, b) RT, 18 h; Yield given. Multistep reaction;
参考文献
Boehringer Ingelheim (Canada) Ltd.
Patent: US6242439 B1, 2001 ;
反应条件
diphenylphosphoranyl azide in dichloromethane T=20°C; 2.5 h;
参考文献
Ma, Bin; Lee, Wen-Cherng
Tetrahedron Letters, 2010 , vol. 51, # 2 p. 385 - 386
反应条件
in ethyl acetate T=45°C; 1 h;
参考文献
Bristol-Myers Squibb Co.
Patent: US6335324 B1, 2002 ;
Location in patent: Page column 56 ;
US 6335324 B1
反应条件
sodium trimethyl-silanolate in tetrahydrofuran; toluene T=0 - 20°C; 0.333333 h;
参考文献
Ma, Bin; Lee, Wen-Cherng
Tetrahedron Letters, 2010 , vol. 51, # 2 p. 385 - 386
反应条件
sodium trimethyl-silanolate in tetrahydrofuran; toluene T=0 - 20°C; 0.333333 h;
参考文献
Ma, Bin; Lee, Wen-Cherng
Tetrahedron Letters, 2010 , vol. 51, # 2 p. 385 - 386
